Cytokine Blood Filtration Responses in COVID-19

The real issue with the COVID-19 pandemic is that a rapidly increasing number of patients with life-threatening complications are admitted in hospitals and are not well-administered. Although a limited number of patients use the intensive care unit (ICU), they consume medical resources, safety equip...

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Bibliographic Details
Published in:Blood Purification 2021, Vol.50 (2), p.141-149
Main Authors: AL Shareef, Khaled, Bakouri, Mohsen
Format: Article
Language:English
Subjects:
Acute Kidney Injury - etiology
Acute Kidney Injury - therapy
Anti-Bacterial Agents - therapeutic use
Coated Materials, Biocompatible
Combined Modality Therapy
Continuous Renal Replacement Therapy
COVID-19 - blood
COVID-19 - complications
Cross-Over Studies
Cytokine Release Syndrome - blood
Cytokine Release Syndrome - etiology
Cytokine Release Syndrome - therapy
Cytokines - blood
Double-Blind Method
Equipment Design
Hemofiltration - instrumentation
Hemofiltration - methods
Humans
Membranes, Artificial
Microspheres
Multiple Organ Failure - etiology
Multiple Organ Failure - therapy
Plasmapheresis - methods
Randomized Controlled Trials as Topic
Respiration, Artificial
Respiratory Distress Syndrome - etiology
Respiratory Distress Syndrome - therapy
Review
SARS-CoV-2
Shock, Septic - blood
Shock, Septic - etiology
Shock, Septic - therapy
Sorption Detoxification - instrumentation
Sorption Detoxification - methods
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Summary:The real issue with the COVID-19 pandemic is that a rapidly increasing number of patients with life-threatening complications are admitted in hospitals and are not well-administered. Although a limited number of patients use the intensive care unit (ICU), they consume medical resources, safety equipment, and enormous equipment with little possibility of rapid recovery and ICU discharge. This work reviews effective methods of using filtration devices in treatment to reduce the level of various inflammatory mediators and discharge patients from the ICU faster. Extracorporeal technologies have been reviewed as a medical approach to absorb cytokines. Although these devices do not kill or remove the virus, they are a promising solution for treating patients and their faster removal from the ICU, thus relieving the bottleneck.
ISSN:0253-5068
1421-9735
DOI:10.1159/000508278