Co‐infection of other respiratory pathogens and HIV in COVID‐19 patients: is there a pattern?

The pandemic caused by SARS‐Cov‐2 has led to the elaboration of multiple studies to increase knowledge and understanding, hence, having the ability to accomplish an adequate and timely diagnosis and give an optimal treatment according to the patient's condition. The clinical manifestations of C...

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Bibliographic Details
Published in:Journal of Medical Virology 2020
Main Authors: Pedro Barrera‐López, Erika D. Pérez‐Riveros, José Moreno‐Montoya, Ballesteros, Silvia Marcela, Valencia, Sergio A, José A. De la Hoz‐Valle
Format: Web Resource
Language:English
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Summary:The pandemic caused by SARS‐Cov‐2 has led to the elaboration of multiple studies to increase knowledge and understanding, hence, having the ability to accomplish an adequate and timely diagnosis and give an optimal treatment according to the patient's condition. The clinical manifestations of COVID‐19 pose a series of challenges both in understanding and delimiting the disease secondary to the SARS‐CoV‐2 infection. This is due to the fact that the main axis of this disease is the endothelial compromise and the production of a "cytokine storm", triggering multiple organ failure and death. Given that a complete understanding of its pathophysiology and clinical behavior has not yet been achieved, we wondered if co‐infection with other respiratory viruses modifies its performance and outcomes described so far. A literature search was performed, obtaining 68 articles, of which 25 were analyzed. The analysis showed us that there is a high variety both in the types of associated infections and in the clinical behavior of patients and their outcomes. Therefore, we consider that the search for other infections should be performed exhaustively, especially in those cases that may be susceptible to treatment such as Influenza A, HIV, or bacterial infections. As well as optimize the analysis of these cases and establish if there are characteristics that allow establishing the possibility of carrying an additional infection to that of SARSCoV2 and the implications for the management and prognosis of the patient.
DOI:10.1002/jmv.26331