MCP-1 causes leukocyte recruitment and subsequently endotoxemic ileus in rat

Endotoxemia causes an inflammatory response within the intestinal muscularis and gastrointestinal dysmotility. We hypothesize that the resident macrophage-derived chemokine monocyte chemoattractant protein-1 (MCP-1) plays a significant role in the recruitment of leukocytes into the lipopolysaccharid...

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Bibliographic Details
Published in:American journal of physiology: Gastrointestinal and liver physiology 2002, Vol.45 (1), p.G145-G155
Main Authors: TÜRLER, Andreas, SCHWARZ, Nicolas T, TÜRLER, Esther, KALFF, Jörg C, BAUER, Anthony J
Format: Article
Language:English
Subjects:
Bacterial diseases
Biological and medical sciences
Experimental bacterial diseases and models
Infectious diseases
Large intestine
Leukocytes
Medical sciences
Rodents
Small intestine
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Summary:Endotoxemia causes an inflammatory response within the intestinal muscularis and gastrointestinal dysmotility. We hypothesize that the resident macrophage-derived chemokine monocyte chemoattractant protein-1 (MCP-1) plays a significant role in the recruitment of leukocytes into the lipopolysaccharide (LPS)-stimulated rat intestinal muscularis.
ISSN:0193-1857
1522-1547