Vulval Cancer: When should I Stop Resecting? Identifying the Factors that Predict Recurrence

Abstract Context: Vulval cancer surgery has become more conservative and it is important to understand whether resection margins alone influence recurrence rates or whether other prognostic factors should be considered when planning treatment. Aims: The aim of this study is to define factors that pr...

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Bibliographic Details
Published in:Indian journal of medical and paediatric oncology 2019-07, Vol.40 (3), p.358-364
Main Authors: Platt, Sarah Louise, Newton, Claire Louise, Humphrey, Pauline J, Pawade, Joya P, Nama, Vivek V
Format: Article
Language:English
Subjects:
Biopsy
Cancer therapies
Decision making
Dissection
Genital cancers
Gynecology
Lymphatic system
Original Article
Pathology
Patients
Radiation therapy
Squamous cell carcinoma
Studies
Surgery
Tumors
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Summary:Abstract Context: Vulval cancer surgery has become more conservative and it is important to understand whether resection margins alone influence recurrence rates or whether other prognostic factors should be considered when planning treatment. Aims: The aim of this study is to define factors that predict vulval cancer recurrence, enabling development of a recurrence prediction model. Settings and Design: This was a Aretrospective descriptive analysis of new vulval squamous cell carcinoma cases in a gynecological oncology center (January 1, 2007 to December 31, 2013). Subjects and Methods: Analysis of tumor characteristics and treatments. Patient outcomes were recorded, identifying recurrences, and subsequent interventions. Statistical Analysis Used: Univariable and multivariable logistic regression tools applied to determine recurrence risk factors. Results: Seventy patients underwent primary vulval surgery. Bilateral groin node dissection was performed in 26/70 (37.1%) cases and unilateral groin node dissection in 9/70 (12.9%) cases. 57/70 (82%) cases had a negative vulval resection margin, with 67%
ISSN:0971-5851
0975-2129
DOI:10.4103/ijmpo.ijmpo_138_17