Genotoxicity of the vegetables juice grown in garden built on the tailings coal deposits

The aim of the present study was to evaluate the genotoxic effect of lettuce (Lactuca sativa L.), beet (Beta vulgaris L.), broccoli (Brassica oleracea var. italica), and kale (Brassica oleracea var. acephala) grown in vegetable garden built on the deposits of coal tailings. For this, we used 72 heal...

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Bibliographic Details
Published in:Archives of environmental & occupational health 2019-11, Vol.74 (6), p.358-363
Main Authors: Zocche, Jairo José, da Conceição Martins, Miriam, Rohr, Paula, Damiani, Adriani Paganini, Teixeira, Karina O., Borges, Gabriela D., de Jesus, Maiellen M., Vilela, Thais Ceresér, de Andrade, Vanessa Moraes
Format: Article
Language:English
Subjects:
Animals
Bioassays
Brassica
Broccoli
Cerebral cortex
Coal
Coal - toxicity
Coal mines
Coal mining
Comet Assay
Damage detection
Deoxyribonucleic acid
DNA
DNA damage
DNA Damage - drug effects
DNA Damage - genetics
Gardens & gardening
Genotoxicity
Health risks
Juices
Male
Mice
Mine tailings
Mutagenicity Tests
Mutagens - toxicity
Organs
Vegetables
Vegetables - genetics
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Summary:The aim of the present study was to evaluate the genotoxic effect of lettuce (Lactuca sativa L.), beet (Beta vulgaris L.), broccoli (Brassica oleracea var. italica), and kale (Brassica oleracea var. acephala) grown in vegetable garden built on the deposits of coal tailings. For this, we used 72 healthy male Swiss albino mice that received juice from the vegetables in an acute or chronic treatment. Using comet assay, we determined that acute administration of the juices of all vegetables from the coal-mining area was genotoxic, and increased the DNA damage in the blood, liver, and cerebral cortex of mice. Therefore, the present data suggest that intake of vegetables cultivated over coal waste results in an increase in DNA damage in some organs; this situation may pose a risk to health.
ISSN:1933-8244
2154-4700
DOI:10.1080/19338244.2019.1586633