Salivary thromboplastic activity in diabetics and healthy controls

Coagulative function of saliva derives from the thromboplastin found in saliva. It may establish hemostasis in the mouth. Salivary disfunction and changes in salivary composition and are frequent complications of diabetes. This study investigated the influence of some local etiologic and systemic fa...

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Bibliographic Details
Published in:Clinical oral investigations 2004-03, Vol.8 (1), p.36-39
Main Authors: Yarat, A, Tunali, T, Pisiriciler, R, Akyuz, S, Ipbuker, A, Emekli, N
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Analysis of Variance
Anti-Bacterial Agents - adverse effects
Blood Coagulation - drug effects
Blood Coagulation - physiology
Blood Glucose - analysis
Case-Control Studies
Chi-Square Distribution
Diabetes Mellitus - blood
Diabetes Mellitus - physiopathology
Female
Humans
Hydrogen-Ion Concentration
Male
Middle Aged
Saliva - chemistry
Saliva - secretion
Salivary Proteins and Peptides - physiology
Secretory Rate
Statistics, Nonparametric
Thromboplastin - analysis
Thromboplastin - physiology
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Summary:Coagulative function of saliva derives from the thromboplastin found in saliva. It may establish hemostasis in the mouth. Salivary disfunction and changes in salivary composition and are frequent complications of diabetes. This study investigated the influence of some local etiologic and systemic factors on salivary thromboplastic activity (STA) in diabetics. In this study, cytological smears and biochemical tests were used. STA was measured by Quick's one stage method, serum glucose by the glucose oxidase method, and salivary protein by the method of Lowry. STA was almost the same in the diabetic and control groups. The only statistically significant difference within the diabetic group was found to be due to antibiotic usage. STA, i.e. clotting time, was 30% longer (114 s) ( p
ISSN:1432-6981
1436-3771
DOI:10.1007/s00784-003-0237-0