The Hancock Alkaloids Angustureine, Cuspareine, Galipinine, and Galipeine: A Review of their Isolation, Synthesis, and Spectroscopic Data

A review of the isolation, reported methods for the synthesis (up to the end of 2018), and spectroscopic data of angustureine, cuspareine, galipinine, and galipeine, members of the Hancock family of alkaloids based upon a 2‐substituted N(1)‐methyl‐1,2–3,4‐tetrahydroisolquinoline scaffold, is present...

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Bibliographic Details
Published in:European journal of organic chemistry 2019-09, Vol.2019 (31-32), p.5093-5119
Main Authors: Davies, Stephen G., Fletcher, Ai M., Roberts, Paul M., Thomson, James E.
Format: Article
Language:English
Subjects:
Alkaloids
Angustureine
Cuspareine
Galipeine
Galipinine
Spectroscopy
Synthesis
Total synthesis
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Summary:A review of the isolation, reported methods for the synthesis (up to the end of 2018), and spectroscopic data of angustureine, cuspareine, galipinine, and galipeine, members of the Hancock family of alkaloids based upon a 2‐substituted N(1)‐methyl‐1,2–3,4‐tetrahydroisolquinoline scaffold, is presented. A review of the isolation, recent reported methods for the synthesis, and spectroscopic data of angustureine, cuspareine, galipinine, and galipeine, members of the Hancock family of alkaloids based upon a 2‐substituted N(1)‐methyl‐1,2–3,4‐tetrahydroisolquinoline scaffold, is presented.
ISSN:1434-193X
1099-0690
DOI:10.1002/ejoc.201900493