Identification of proteins for controlled nucleation of metal-organic crystals for nanoenergetics

Here, we report that a marine sandworm Nereis virens jaw protein, Nvjp1, nucleates hemozoin with similar activity as the native parasite hemozoin protein, HisRPII. X-ray diffraction and scanning electron microscopy confirm the identity of the hemozoin produced from Nvjp1-containing reactions. Finall...

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Bibliographic Details
Published in:MRS communications 2019-06, Vol.9 (2), p.456-463
Main Authors: Reinert, Zachary E., Hung, Chia-Suei, Poole, Andrea R., Slocik, Joseph M., Crosby, Marquise G., Singamaneni, Srikanth, Naik, Rajesh R., Dennis, Patrick B., Crookes-Goodson, Wendy J., Gupta, Maneesh K.
Format: Article
Language:English
Subjects:
Aluminum
Biomaterials
Characterization and Evaluation of Materials
Deoxyribonucleic acid
DNA
Heat
Malaria
Materials Engineering
Materials Science
Mechanical properties
Nanomaterials
Nanoparticles
Nanotechnology
Nucleation
Organic crystals
Parasites
Peptides
Polymer Sciences
Proteins
Scanning electron microscopy
Spectrum analysis
Synthetic Biology Research Letter
Synthetic Biology Research Letters
X-ray diffraction
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Summary:Here, we report that a marine sandworm Nereis virens jaw protein, Nvjp1, nucleates hemozoin with similar activity as the native parasite hemozoin protein, HisRPII. X-ray diffraction and scanning electron microscopy confirm the identity of the hemozoin produced from Nvjp1-containing reactions. Finally, we observed that nAl assembled with hemozoin from Nvjp1 reactions has a substantially higher energetic output when compared to analogous thermite from the synthetic standard or HisRPII-nucleated hemozoin. Our results demonstrate that a marine sandworm protein can nucleate malaria pigment and set the stage for engineering recombinant hemozoin production for nanoenergetic applications.
ISSN:2159-6859
2159-6867
DOI:10.1557/mrc.2019.46