Body mass index and the risk of head and neck cancer in the Chinese population

•Low body mass index, even at age 20, was associated with a higher risk of HNC.•Being obese was associated with a lower risk of HNC.•BMI loss was also an important risk factor for HNC. To investigate potential associations between body mass index (BMI) and head and neck cancer (HNC) risk in an East...

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Bibliographic Details
Published in:Cancer epidemiology 2019-06, Vol.60, p.208-215
Main Authors: Chen, Yuji, Lee, Yuan-Chin Amy, Li, Shuang, Li, Qian, Chen, Chien-Jen, Hsu, Wan-Lun, Lou, Pen-Jen, Zhu, Cairong, Pan, Jian, Shen, Hongbing, Ma, Hongxia, Cai, Lin, He, Baochang, Wang, Yu, Zhou, Xiaoyan, Ji, Qinghai, Zhou, Baosen, Wu, Wei, Ma, Jie, Kawakita, Daisuke, Boffetta, Paolo, Zhang, Zuo-Feng, Dai, Min, Hashibe, Mia
Format: Article
Language:English
Subjects:
Adult
Age
Aged
Aged, 80 and over
Alcohol
Asian Continental Ancestry Group
BMI
Body mass
Body Mass Index
Body size
Cancer
Case-Control Studies
Confidence intervals
East Asia
Epidemiology
Female
Head & neck cancer
Head and neck cancer risk
Head and Neck Neoplasms - etiology
Health risks
Humans
Interviews
Larynx
Male
Middle Aged
Obesity
Population
Risk
Risk Factors
Smoking
Statistical analysis
Tobacco
Underweight
Young Adult
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Summary:•Low body mass index, even at age 20, was associated with a higher risk of HNC.•Being obese was associated with a lower risk of HNC.•BMI loss was also an important risk factor for HNC. To investigate potential associations between body mass index (BMI) and head and neck cancer (HNC) risk in an East Asian population. We conducted a hospital-based multicenter case-control study in East Asia including 921 cases and 806 controls. We estimated the odds ratios (ORs) and 95% confidence intervals (95% CI) for HNC risks by using logistic regression, adjusting on potential confounders. Compared to normal BMI at interview (18.5–
ISSN:1877-7821
1877-783X
DOI:10.1016/j.canep.2019.04.008