Reflection-Based Thin-Core Modal Interferometry Optical Fiber Functionalized With PAA-PBA/PVA for Glucose Detection Under Physiological pH

A phenylboronic-acid-derivatized poly (acrylic acid) (PAA-PBA)/poly(vinyl alcohol) (PVA) functionalized thin-core fiber (TCF) optical sensor is proposed for glucose detection. The unique Michelson-type fiber interferometer sensor was fabricated by splicing a short segment of TCF with a single-mode f...

Full description

Saved in:
Bibliographic Details
Published in:Journal of lightwave technology 2019-06, Vol.37 (11), p.2773-2777
Main Authors: Yan Ru Wang, Zhi Qiang Tou, Ravikumar, Raghunandhan, Yi Yin Lim, Zhe Wen Ding, Chun Liu Zhao, Ping Lam So, Chi Chiu Chan
Format: Article
Language:English
Subjects:
Acrylic acid
Biological sensing and sensors
Fiber optics
Glucose
Insulin
multilayer design
Multilayers
Optical fiber cables
Optical fiber sensors
Optical fibers
Optical measuring instruments
Optics
Physiology
polymers
Probes
Reagents
Reflectivity
Refractive index
Selectivity
Sensors
Splicing
Sugar
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A phenylboronic-acid-derivatized poly (acrylic acid) (PAA-PBA)/poly(vinyl alcohol) (PVA) functionalized thin-core fiber (TCF) optical sensor is proposed for glucose detection. The unique Michelson-type fiber interferometer sensor was fabricated by splicing a short segment of TCF with a single-mode fiber, where the tip of TCF was melted into a rounded shape. PAA-PBA was synthesized by grafting PBA onto the PAA chain using N-hydroxysuccinimide and 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride as coupling reagent. Multilayer films of PAA-PBA and PVA were subsequently functionalized onto the fiber-optic Michelson interferometer structure through layer-by-layer assembly. Experiments showed that the PAA-PBA/PVA functionalized fiber-optic probe exhibits glucose-sensitive behavior under physiological pH. The proposed sensor offers benefits such as simple fabrication, compact size, and glucose selectivity and has potential applications, such as insulin release system, in a biodevice.
ISSN:0733-8724
1558-2213
DOI:10.1109/JLT.2018.2879318