Diffusion MR findings in cyclosporin-A induced encephalopathy

Cyclosporin encephalopathy is a well-known entity, which is clinically characterized by altered mental status, vision problems, focal neurological deficits and seizures. The exact pathophysiology of the cyclosporin encephalopathy has not yet been defined. We report the diffusion-weighted MR imaging...

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Bibliographic Details
Published in:Neuroradiology 2004-10, Vol.46 (10), p.822
Main Authors: Aydin, Kubilay, Donmez, Fuldem, Tuzun, Umit, Minareci, Ozenc, Atamer, Tanju
Format: Article
Language:English
Subjects:
Adult
Brain
Brain - metabolism
Brain - pathology
Brain Diseases - chemically induced
Brain Diseases - diagnosis
Cyclosporine - antagonists & inhibitors
Diffusion Magnetic Resonance Imaging
Disease
Humans
Immunosuppressive Agents - antagonists & inhibitors
Magnetic Resonance Spectroscopy
Male
Medical imaging
NMR
Nuclear magnetic resonance
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Summary:Cyclosporin encephalopathy is a well-known entity, which is clinically characterized by altered mental status, vision problems, focal neurological deficits and seizures. The exact pathophysiology of the cyclosporin encephalopathy has not yet been defined. We report the diffusion-weighted MR imaging and proton MR spectroscopy findings in a case of cyclosporin encephalopathy. The white-matter lesions with reversible restricted diffusion supported the hypothesis of reversible vasospasm induced by the cyclosporin.
ISSN:0028-3940
1432-1920
DOI:10.1007/s00234-004-1258-3