Design, fabrication, and characterization of polycaprolactone (PCL)-TiO2-collagenase nanofiber mesh scaffolds by Forcespinning

We report on the design of polycaprolactone (PCL)-TiO2-collagenase mesh scaffolds by Forcespinning technique. The dependence of the degree of crystallinity in PCL caused by the incorporation of dopants (TiO2-collagenase) and the reduction of dimensionality (1D), during the nanofiber formation, were...

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Bibliographic Details
Published in:MRS communications 2019-03, Vol.9 (1), p.390-397
Main Authors: del Ángel-Sánchez, K., Ulloa-Castillo, N.A., Segura-Cárdenas, Emmanuel, Martinez-Romero, Oscar, Elías-Zuñiga, Alex
Format: Article
Language:English
Subjects:
Acids
Biomaterials
Biomedical materials
Biopolymers
Cell growth
Characterization and Evaluation of Materials
Chemical industry
Collagen
Contact angle
Degree of crystallinity
Dependence
Fourier transforms
Hydrophobicity
Materials Engineering
Materials Science
Morphology
Nanofibers
Nanoparticles
Nanotechnology
Polycaprolactone
Polymer Sciences
Polyvinyl alcohol
Research Letter
Research Letters
Scaffolds
Spectrum analysis
Test equipment
Tissue engineering
Titanium
Titanium dioxide
Ultrasonic testing
Uniaxial tests
X-ray diffraction
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Summary:We report on the design of polycaprolactone (PCL)-TiO2-collagenase mesh scaffolds by Forcespinning technique. The dependence of the degree of crystallinity in PCL caused by the incorporation of dopants (TiO2-collagenase) and the reduction of dimensionality (1D), during the nanofiber formation, were investigated by x-ray diffraction and differential scanning calorimetry. The tensile strength of the mesh scaffolds (randomly oriented) was determined using uniaxial testing equipment. The permeability was measured by contact angle obtaining an improvement in the hydrophobicity for the PCL-TiO2-collagenase mesh scaffolds. The results reported in this research are of great relevance for tissue engineering applications.
ISSN:2159-6859
2159-6867
DOI:10.1557/mrc.2019.13