Rapid Interception of CnF2n+1(O)SO. Radical with Copper‐Based Carbene: A Novel Access to Perfluoroalkanesulfinate Ester

In this communication, an unprecedented interception of CnF2n+1(O)SO. radical with a copper‐based carbene has been established. Distinguished by wide substrate scopes and mild reaction conditions, this novel radical–carbene coupling reaction (RCC reaction) provides a fundamentally different and mech...

Full description

Saved in:
Bibliographic Details
Published in:Chemistry : a European journal 2019-02, Vol.25 (9), p.2195-2198
Main Authors: Wang, Hanghang, Li, Haiyan, Zheng, Yonggao, Lian, Pengcheng, Wan, Xiaobing
Format: Article
Language:English
Subjects:
carbenes
Chemical industry
Chemical synthesis
Chemistry
Copper
Esters
Interception
organic synthesis
radical coupling
radicals
Substrates
synthetic methods
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In this communication, an unprecedented interception of CnF2n+1(O)SO. radical with a copper‐based carbene has been established. Distinguished by wide substrate scopes and mild reaction conditions, this novel radical–carbene coupling reaction (RCC reaction) provides a fundamentally different and mechanistically interesting strategy for the synthesis of perfluoroalkanesulfinate esters. Better be quick! Through rapid interception of CnF2n+1(O)SO. radical with a copper‐based carbene, a fundamentally different and mechanistically interesting synthetic strategy for perfluoroalkanesulfinate esters has been developed. This novel radical–carbene coupling reaction (RCC reaction) is distinguished by wide substrate scopes, short reaction time, mild reaction conditions, and operational simplicity, leading to a variety of perfluoroalkanesulfinate esters in satisfactory yields.
ISSN:0947-6539
1521-3765
DOI:10.1002/chem.201805639