Intraplacental retinol distribution

With the objective of evaluating intraplacental vitamin A distribution, 234 placental samples were collected, corresponding to six samples from each of the placentas analyzed: two from the lateral maternal portion, one from the central maternal portion, two from the lateral fetal portion, and one fr...

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Bibliographic Details
Published in:International journal of food sciences and nutrition 2005-12, Vol.56 (8), p.607-612
Main Authors: Saunders, C, Leal, M. do C, Flores, H, Soares, A.G, Lima, A.P.P.T. de, Leite, P.C, Gomes, M.M, Souza Júnior, P.R.B. de, Ramalho, R.A
Format: Article
Language:English
Subjects:
Adolescent
Adult
Biological and medical sciences
Brazil
Embryology: invertebrates and vertebrates. Teratology
Female
Fetal membranes
Fetuses
Food science
Fundamental and applied biological sciences. Psychology
General aspects. Development. Fetal membranes
histochemistry
Humans
Maternal-Fetal Exchange
maternal-fetal transfer
Mothers
Nutritional Status
placenta
Placenta - chemistry
Postpartum Period
postpartum women
Pregnancy
Reference Values
retinol
spatial variation
Specimen Handling - methods
spectroscopy
Vitamin A
Vitamin A - analysis
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Summary:With the objective of evaluating intraplacental vitamin A distribution, 234 placental samples were collected, corresponding to six samples from each of the placentas analyzed: two from the lateral maternal portion, one from the central maternal portion, two from the lateral fetal portion, and one from the central fetal portion. Samples were obtained from 39 adult puerperal mothers with low-risk pregnancies, without vitamin A deficiency or night blindness. Retinol content determination was achieved through spectrophotometry. Retinol values obtained for each region were correlated with the most probable value for each placenta (P < 0.001). Despite differences in retinol content between samples, statistical data analysis showed that intra-tissue variation had no influence on the conversion of data into information. Consequently, any portion of the placenta may be used for retinol level determination purposes, due to the correlation between all portions and the most probable value. The findings of the present study represent an advance for surveys intending to incorporate the collection and dosage of placental vitamin A levels into their analyses, thus increasing the arsenal of pre-pathological or subclinical vitamin A deficiency markers, which can allow for earlier intervention on the maternal-infant group.
ISSN:0963-7486
1465-3478
DOI:10.1080/09637480500524281