Nd3+ doped LaF3 nanoparticles as self-monitored photo-thermal agents

In this work, we demonstrate how LaF3 nanoparticles activated with large concentrations (up to 25%) of Nd3+ ions can simultaneously operate as biologically compatible efficient nanoheaters and fluorescent nanothermometers under single beam (808 nm) infrared laser excitation. Nd3+:LaF3 nanoparticles...

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Bibliographic Details
Published in:Applied physics letters 2014-02, Vol.104 (5)
Main Authors: Rocha, Uéslen, Upendra Kumar, K., Jacinto, Carlos, Ramiro, Julio, Caamaño, Antonio J., García Solé, José, Jaque, Daniel
Format: Article
Language:English
Subjects:
Applied physics
Fluorescence
Infrared lasers
Lanthanum fluorides
Laser beams
Nanoparticles
Thermal imaging
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Summary:In this work, we demonstrate how LaF3 nanoparticles activated with large concentrations (up to 25%) of Nd3+ ions can simultaneously operate as biologically compatible efficient nanoheaters and fluorescent nanothermometers under single beam (808 nm) infrared laser excitation. Nd3+:LaF3 nanoparticles emerge as unique multifunctional agents that could constitute the first step towards the future development of advanced platforms capable of simultaneous deep tissue fluorescence bio-imaging and controlled photo-thermal therapies.
ISSN:0003-6951
1077-3118
DOI:10.1063/1.4862968