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Ventricular bigeminal rhythm associated with trastuzumab: A potential cardiac side effect
Cardiac side effects of targeted chemotherapy agents are getting more and more important topic nowadays. However, the studies on this topic are limited. Because multiple agent chemotherapy is not a common treatment option, it is hard to establish controlled study groups (as before chemotherapy and a...
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| Published in: | Journal of cancer research and therapeutics 2018-06, Vol.14 (9), p.536-537 |
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| Main Authors: | , , , , , , , , |
| Format: | Article |
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| container_end_page | 537 |
| container_issue | 9 |
| container_start_page | 536 |
| container_title | Journal of cancer research and therapeutics |
| container_volume | 14 |
| creator | Karaca, Mustafa Kocoglu, Hakan Bilgetekin, Irem Ozet, Ahmet Sahinli, Hayriye Demir, Hacer Kankoc, Aykut Tural, Deniz Yucel, Orhan |
| description | Cardiac side effects of targeted chemotherapy agents are getting more and more important topic nowadays. However, the studies on this topic are limited. Because multiple agent chemotherapy is not a common treatment option, it is hard to establish controlled study groups (as before chemotherapy and after chemotherapy); further, cancer, itself, may cause cardiac side effects and uncertainty of the symptoms may be associated with previous clinical situation before chemotherapy. For all that, we may get information to a certain degree about the side effects of these agents by analyzing case reports. These side effects have a broad spectrum from asymptomatic rhythm alterations to acute cardiac death. In this case report, we aim to discuss asymptomatic ventricular bigeminal rhythm, which is proved by electrocardiography, of our patient during treated by trastuzumab. |
| doi_str_mv | 10.4103/0973-1482.183557 |
| format | article |
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However, the studies on this topic are limited. Because multiple agent chemotherapy is not a common treatment option, it is hard to establish controlled study groups (as before chemotherapy and after chemotherapy); further, cancer, itself, may cause cardiac side effects and uncertainty of the symptoms may be associated with previous clinical situation before chemotherapy. For all that, we may get information to a certain degree about the side effects of these agents by analyzing case reports. These side effects have a broad spectrum from asymptomatic rhythm alterations to acute cardiac death. 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However, the studies on this topic are limited. Because multiple agent chemotherapy is not a common treatment option, it is hard to establish controlled study groups (as before chemotherapy and after chemotherapy); further, cancer, itself, may cause cardiac side effects and uncertainty of the symptoms may be associated with previous clinical situation before chemotherapy. For all that, we may get information to a certain degree about the side effects of these agents by analyzing case reports. These side effects have a broad spectrum from asymptomatic rhythm alterations to acute cardiac death. 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| ispartof | Journal of cancer research and therapeutics, 2018-06, Vol.14 (9), p.536-537 |
| issn | 0973-1482 1998-4138 |
| language | eng |
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| source | Publicly Available Content (ProQuest); IngentaConnect Journals |
| subjects | Antineoplastic agents Antineoplastic Agents, Immunological - adverse effects Antineoplastic Agents, Immunological - therapeutic use Antineoplastic Combined Chemotherapy Protocols - adverse effects Antineoplastic Combined Chemotherapy Protocols - therapeutic use Arrhythmias, Cardiac - diagnosis Arrhythmias, Cardiac - etiology Biomarkers Breast cancer Breast Neoplasms - complications Breast Neoplasms - diagnosis Breast Neoplasms - drug therapy Chemotherapy Echocardiography Electrocardiography Female Gene amplification Heart failure Humans Immunotherapy Middle Aged Monoclonal antibodies Patient outcomes Patients Sinuses Targeted cancer therapy Trastuzumab Trastuzumab - adverse effects Trastuzumab - therapeutic use Ultrasonic imaging Ventricular Dysfunction - diagnosis Ventricular Dysfunction - etiology |
| title | Ventricular bigeminal rhythm associated with trastuzumab: A potential cardiac side effect |
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