Skin Pigmentation‐Inspired Polydopamine Sunscreens

Commercial sunscreens usually rely on multiple component formulas against solar irradiation, including UV filters, antioxidants, and nanomaterial matrices. While many efforts are devoted, concern has arisen that the effectiveness and safety issues of most sunscreens are largely limited by their comp...

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Bibliographic Details
Published in:Advanced functional materials 2018-08, Vol.28 (33), p.n/a
Main Authors: Wang, Changping, Wang, Dong, Dai, Tianjiao, Xu, Peng, Wu, Peilun, Zou, Yuan, Yang, Peng, Hu, Jingjing, Li, Yiwen, Cheng, Yiyun
Format: Article
Language:English
Subjects:
Antioxidants
Biocompatibility
Biomimetics
Formulations
Gels
Materials science
Melanin
Nanomaterials
Penetration resistance
polydopamine nanoparticles
Shielding
skin pigmentation
Sun screens
Sunscreen
Toxicity
Ultraviolet filters
Ultraviolet radiation
UV protection
Water resistance
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Summary:Commercial sunscreens usually rely on multiple component formulas against solar irradiation, including UV filters, antioxidants, and nanomaterial matrices. While many efforts are devoted, concern has arisen that the effectiveness and safety issues of most sunscreens are largely limited by their complex formulations, photostability, and toxicity. Inspired by skin pigmentation as primary photoprotective mechanism in human body, novel sunscreen products based on polydopamine (PDA) gels, with a bioinspired protection concept and improved photoprotective capacities, were rationally designed and facilely prepared. The diverse formula of those sunscreen gels can be achieved by the use of PDA nanoparticle, a kind of naturally melanin mimics, to complex/conjugate with different polymers. The resulting PDA sunscreens are bioadhesive, water resistant, and nonskin penetration, yet can be directly removed by towel wiping. They also perform many promising features including superior UV shielding properties, high in vitro and in vivo UV protection efficiencies, nonphototoxicity, and nonirritating nature. These PDA materials in an initial proof‐of‐concept study were described and it is proposed that this class of bioinspired gels will be useful for incident UV protection where simple, safe, and efficient sunscreens are still highly desirable. Inspired by skin pigmentation as primary photoprotective mechanism in human body, novel sunscreen products based on polydopamine (PDA) gels, with a bioinspired protection concept and improved photoprotective capacities, are rationally designed. Those bioinspired sunscreens involve many promising features including superior UV shielding properties, high in vitro and in vivo UV protection efficiencies, nonphototoxicity, and nonirritating nature.
ISSN:1616-301X
1616-3028
DOI:10.1002/adfm.201802127