Liver involvement in kidney disease and vice versa

Liver involvement in kidney disease and vice versa

The liver and kidneys are often similarly affected by a single disease. This is the case in metabolic, immunological, toxic, and infectious diseases, and in the different congenital malformation syndromes. Also, an enzymatic defect in an otherwise healthy liver or the consequences of advanced liver...

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Bibliographic Details
Published in:Pediatric nephrology (Berlin, West) West), 2018-06, Vol.33 (6), p.957-971
Main Authors: Van Hoeve, Karen, Mekahli, Djalila, Morava, Eva, Levtchenko, Elena, Witters, Peter
Format: Article
Language:eng
Subjects:
Causes of
Children
Complications and side effects
Congenital defects
Educational Review
Health aspects
Infectious diseases
Kidney diseases
Kidney transplantation
Kidneys
Liver
Liver diseases
Liver transplantation
Liver transplants
Medicine
Medicine & Public Health
Methods
Nephrology
Pediatrics
Safety and security measures
Transplantation
Urology
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Description
Summary:The liver and kidneys are often similarly affected by a single disease. This is the case in metabolic, immunological, toxic, and infectious diseases, and in the different congenital malformation syndromes. Also, an enzymatic defect in an otherwise healthy liver or the consequences of advanced liver disease by itself can cause kidney disease as a secondary phenomenon. In this review, we describe numerous pathogenic mechanisms leading to dysfunction or malformations of the liver and kidneys in children. We encourage multidisciplinary management for optimal care. A combined liver–kidney transplantation is sometimes needed.
ISSN:0931-041X
1432-198X