Production and Characterization of Antimicrobial Electrospun Nanofibers Containing Polyurethane, Zirconium Oxide and Zeolite

In this study, electrospinning technique has been utilized to prepare composite nanofiber mats of polyurethane (PU)/zirconium dioxide (ZrO 2 ) and PU/zeolite, consisted by antimicrobial properties. Tensile strength measurement test was performed for the mechanical analysis of the nanofibers. Scannin...

Full description

Saved in:
Bibliographic Details
Published in:BioNanoScience 2018-03, Vol.8 (1), p.154-165
Main Authors: Aydogdu, Mehmet Onur, Oprea, Alexandra Elena, Trusca, Roxana, Surdu, Adrian Vasile, Ficai, Anton, Holban, Alina Maria, Iordache, Florin, Paduraru, Andrei Viorel, Filip, Diana Georgiana, Altun, Esra, Ekren, Nazmi, Oktar, Faik Nuzhet, Gunduz, Oguzhan
Format: Article
Language:English
Subjects:
Antiinfectives and antibacterials
Biocompatibility
Biological and Medical Physics
Biomaterials
Biophysics
Cell proliferation
Circuits and Systems
Cytotoxicity
Electron microscopy
Engineering
In vitro methods and tests
Mats
Mechanical analysis
Mechanical properties
Nanofibers
Nanotechnology
Polyurethane
Polyurethane resins
Scanning electron microscopy
Toxicity
Viability
Wound healing
Wounds
Zeolites
Zirconium dioxide
Zirconium oxides
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In this study, electrospinning technique has been utilized to prepare composite nanofiber mats of polyurethane (PU)/zirconium dioxide (ZrO 2 ) and PU/zeolite, consisted by antimicrobial properties. Tensile strength measurement test was performed for the mechanical analysis of the nanofibers. Scanning electron microscopy (SEM) were performed for displaying the morphological features of the fiber structure. XRD tests were performed for revealing the chemical structure. Antimicrobial tests were also performed to display antimicrobial effects of the produced materials. In vitro test was also performed to determine cytotoxicity and biocompatibility. The present PU/ZrO 2 and PU/zeolite composite nanofibers resulted with improved mechanical properties and good antimicrobial properties against either their pure forms or other studies. Cell proliferation and viability also increased significantly with increase in zeolite and ZrO 2 ratio. It is concluded that this composition provides a novel alternative as an antimicrobial material which can be suitable as a wound dressing or a coating material for various healthcare engineering applications.
ISSN:2191-1630
2191-1649
DOI:10.1007/s12668-017-0443-x