Approximation of the Dependency of Trace Elements Concentrations in Internal Media upon their Contents in Environment Objects

Models that demonstrate the dependency of a trace element content in the internal milieu of an organism upon that in external media objects of the environment were developed to identify dominant factors in ecology-mediated microelement imbalance in a human body. Based on the sets of experimental dat...

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Bibliographic Details
Published in:BioNanoScience 2018-03, Vol.8 (1), p.288-295
Main Authors: Alekseevna, Tunakova Yulia, Vladimirovna, Novikova Svetlana, Iskanderovich, Faizullin Rashat, Sergeevich, Valiev Vsevolod
Format: Article
Language:English
Subjects:
Approximation
Bioaccumulation
Biological and Medical Physics
Biomaterials
Biophysics
Body fluids
Circuits and Systems
Computational fluid dynamics
Drinking water
Engineering
Environment models
Human body
Isotopes
Mathematical analysis
Media
Nanotechnology
Snow cover
Soil water
Trace elements
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Summary:Models that demonstrate the dependency of a trace element content in the internal milieu of an organism upon that in external media objects of the environment were developed to identify dominant factors in ecology-mediated microelement imbalance in a human body. Based on the sets of experimental data obtained on trace element concentrations in the internal milieu (fluids) of a human body (blood) and accumulating media (hair), external fluids (drinking water), and deposit media (soil and snow cover), the degree of approximation of dependencies captured with different models was estimated, with the most adequate ones chosen. Linear, cubic, logistic, sigmoidal, parabolic functions, a polynomial of the fourth and fifth degrees, the Nelder–Mead optimization algorithm, and a Boltzmann function were applied to evaluate the approximation degree by different models. The selection of internal and external media demonstrating the best approximation results is justified.
ISSN:2191-1630
2191-1649
DOI:10.1007/s12668-017-0487-y