Stenotrophomonas maltophilia : an emerging opportunist human pathogen

Summary Stenotrophomonas maltophilia has emerged as an important opportunistic pathogen in the debilitated host. S maltophilia is not an inherently virulent pathogen, but its ability to colonise respiratory-tract epithelial cells and surfaces of medical devices makes it a ready coloniser of hospital...

Full description

Saved in:
Bibliographic Details
Published in:The Lancet infectious diseases 2009-05, Vol.9 (5), p.312-323
Main Authors: Looney, W John, CSci FIBMS, Narita, Masashi, MD, Mühlemann, Kathrin, MD
Format: Article
Language:English
Subjects:
Bacterial diseases
Bacterial diseases of the respiratory system
Bacterial sepsis
Biological and medical sciences
Communicable Diseases, Emerging - diagnosis
Communicable Diseases, Emerging - drug therapy
Communicable Diseases, Emerging - microbiology
Drug Resistance, Multiple, Bacterial
Environmental Exposure
Gram-Positive Bacterial Infections - diagnosis
Gram-Positive Bacterial Infections - drug therapy
Gram-Positive Bacterial Infections - microbiology
Human bacterial diseases
Humans
Infectious Disease
Infectious diseases
Medical sciences
Microbial Sensitivity Tests
Opportunistic Infections - diagnosis
Opportunistic Infections - drug therapy
Opportunistic Infections - microbiology
Stenotrophomonas maltophilia - classification
Stenotrophomonas maltophilia - drug effects
Stenotrophomonas maltophilia - pathogenicity
Trimethoprim, Sulfamethoxazole Drug Combination - therapeutic use
Water Microbiology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Summary Stenotrophomonas maltophilia has emerged as an important opportunistic pathogen in the debilitated host. S maltophilia is not an inherently virulent pathogen, but its ability to colonise respiratory-tract epithelial cells and surfaces of medical devices makes it a ready coloniser of hospitalised patients. S maltophilia can cause blood-stream infections and pneumonia with considerable morbidity in immunosuppressed patients. Management of infection is hampered by high-level intrinsic resistance to many antibiotic classes and the increasing occurrence of acquired resistance to the first-line drug co-trimoxazole. Prevention of acquisition and infection depends upon the application of modern infection-control practices, with emphasis on the control of antibiotic use and environmental reservoirs.
ISSN:1473-3099
1474-4457
DOI:10.1016/S1473-3099(09)70083-0