MARKEDLY ELEVATED PERICARDIAL FLUID LEVELS OF PERIOSTIN ARE INVOLVED IN LEFT VENTRICULAR DYSFUNCTION WITH CORONARY ARTERY DISEASE

Methods With an electrochemiluminescent immunoassay, we measured the concentrations of periostin in serum and pericardial fluid simultaneously in 79 patients undergoing coronary artery bypass grafting consisting of mild ischemia group (MI group, n=36) and severe ischemia group (SI group, n=43). Conc...

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Bibliographic Details
Published in:Journal of the American College of Cardiology 2018-03, Vol.71 (11), p.A768
Main Authors: Miyamoto, Shoichi, Izumi, Toshiaki, Haruna, Yoshizumi, Nakane, Eisaku, Hayashi, Hideyuki, Seko, Yuta, Nakasone, Kazutaka, Kimura, Kouki, Nishiwaki, Shushi, Hamaguchi, Touka, Takai, Fumie, Morishima, Manabu, Haruna, Tetsuya, Inoko, Moriaki, Hanyu, Michiya, Fujita, Masatoshi
Format: Article
Language:English
Subjects:
Beta blockers
Cardiology
Cardiovascular disease
Coronary artery
Coronary artery disease
Coronary vessels
Heart
Heart diseases
Heart surgery
Ischemia
Ventricle
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Summary:Methods With an electrochemiluminescent immunoassay, we measured the concentrations of periostin in serum and pericardial fluid simultaneously in 79 patients undergoing coronary artery bypass grafting consisting of mild ischemia group (MI group, n=36) and severe ischemia group (SI group, n=43). Conclusion Increased PF concentrations of periostin reflect the direct actions as a local mediator against cardiac remodeling in CAD patients with left ventricular systolic dysfunction.
ISSN:0735-1097
1558-3597
DOI:10.1016/S0735-1097(18)31309-3