Primary medical therapy for acromegaly

Summary There is now considerable evidence that the clinical outcome in patients with acromegaly can be improved very substantially by means of better surgical expertise and effective medical therapies used in a flexible and innovative manner. Medical therapy alone in patients who have not undergone...

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Bibliographic Details
Published in:Clinical endocrinology (Oxford) 2003-04, Vol.58 (4), p.387-399
Main Author: Sheppard, Michael C.
Format: Article
Language:English
Subjects:
Acromegaly - drug therapy
Acromegaly - mortality
Acromegaly - surgery
Adenoma - drug therapy
Adenoma - mortality
Adenoma - surgery
Biological and medical sciences
Cholelithiasis - chemically induced
Combined Modality Therapy
Delayed-Action Preparations
Growth Hormone - antagonists & inhibitors
Growth Hormone - metabolism
Hormones. Endocrine system
Human Growth Hormone - analogs & derivatives
Human Growth Hormone - therapeutic use
Humans
Insulin-Like Growth Factor I - metabolism
Medical sciences
Octreotide - therapeutic use
Pharmacology. Drug treatments
Pituitary Neoplasms - drug therapy
Pituitary Neoplasms - mortality
Pituitary Neoplasms - surgery
Receptors, Somatotropin - antagonists & inhibitors
Somatostatin - analogs & derivatives
Somatostatin - therapeutic use
Treatment Outcome
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Summary:Summary There is now considerable evidence that the clinical outcome in patients with acromegaly can be improved very substantially by means of better surgical expertise and effective medical therapies used in a flexible and innovative manner. Medical therapy alone in patients who have not undergone surgery or radiotherapy (primary medical therapy) offers the prospect of near normalisation of GH/IGF‐I levels together with substantial tumour shrinkage in a significant number of patients.
ISSN:0300-0664
1365-2265
DOI:10.1046/j.1365-2265.2003.01734.x