An examination of the effect of aerosolized Permanone insecticide on zebra finch susceptibility to West Nile virus

West Nile virus (WNV) is maintained cryptically primarily in avian (passerine) populations, where it is transmitted by Culex spp. mosquitoes. Mosquito‐control measures currently include physical activities to reduce mosquito‐breeding sites and the application of mosquito larvicides or aerosolized in...

Full description

Saved in:
Bibliographic Details
Published in:Environmental toxicology and chemistry 2017-12, Vol.36 (12), p.3376-3386
Main Authors: Jankowski, Mark D., Moore, Murray E., Hofmeister, Erik K.
Format: Article
Language:English
Subjects:
Adults
Aerosols
Agrochemicals
Animals
Aquatic insects
Bird Diseases - immunology
Bird Diseases - physiopathology
Bird Diseases - virology
Birds
Body mass
Breeding sites
Clearing
Disease Susceptibility
Epidemics
Exposure
Finches - virology
Immune system
Immunotoxicity
Insecticide
Insecticide resistance
Insecticides
Insecticides - toxicity
Larvicides
Mosquito Control
Mosquitoes
Organic compounds
Organochlorine pesticides
Permethrin
Permethrin - toxicity
Piperonyl butoxide
Piperonyl Butoxide - toxicity
Populations
Public domain
Pyrethroid
Pyrethroids
Vector-borne diseases
Vertebrates
Viremia
Viremia - virology
Viruses
West Nile Fever - immunology
West Nile Fever - physiopathology
West Nile Fever - veterinary
West Nile Fever - virology
West Nile virus
Zebra finch
Zika Virus
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:West Nile virus (WNV) is maintained cryptically primarily in avian (passerine) populations, where it is transmitted by Culex spp. mosquitoes. Mosquito‐control measures currently include physical activities to reduce mosquito‐breeding sites and the application of mosquito larvicides or aerosolized insecticides to kill adults (adulticides) when arboviral diseases such as WNV or Zika virus are detected in mosquito populations. Organochlorine, organophosphorus, carbamate, and pyrethroid insecticides are often used. Previous work suggests an effect of pyrethroids on the immune system in a variety of vertebrates. We examined the effects of exposure to aerosolized Permanone® 30:30 insecticide (permethrin and piperonyl butoxide in soy oil vehicle) at approximately 103 to 106 times potential environmental concentrations on the response of captive zebra finches (Taeniopygia guttata) to experimental challenge with WNV. Compared to vehicle control birds, WNV outcome was unchanged (65% of birds produced a viremia) in the “low” exposure (9.52 ± 3.13 mg/m3 standard deviation [SD] permethrin) group but reduced in the “high” exposure (mean 376.5 ± 27.9 mg/m3 SD permethrin) group (30% were viremic; p 
ISSN:0730-7268
1552-8618
DOI:10.1002/etc.3918