Fabrication of SERS active gold nanorods using benzalkonium chloride, and their application to an immunoassay for potato virus X

The authors report on a robust method for the synthesis of gold nanorods (AuNRs) with tunable dimensions and longitudinal surface plasmon resonance. The method relies on seed-mediated particle growth in the presence of benzalkonium chloride (BAC) in place of the widely used surfactant cetyltrimethyl...

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Bibliographic Details
Published in:Mikrochimica acta (1966) 2017-04, Vol.184 (4), p.1059-1067
Main Authors: Caglayan, Mehmet Gokhan, Kasap, Esin, Cetin, Demet, Suludere, Zekiye, Tamer, Ugur
Format: Article
Language:English
Subjects:
Analytical Chemistry
Characterization and Evaluation of Materials
Chemistry
Chemistry and Materials Science
Ethylenediaminetetraacetic acid
Gold
Immunoassay
Microengineering
Nanochemistry
Nanorods
Nanotechnology
Original Paper
Potatoes
Quantitative analysis
Surface active agents
Surfactants
Viruses
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Summary:The authors report on a robust method for the synthesis of gold nanorods (AuNRs) with tunable dimensions and longitudinal surface plasmon resonance. The method relies on seed-mediated particle growth in the presence of benzalkonium chloride (BAC) in place of the widely used surfactant cetyltrimethyl ammonium bromide (CTAB). Uniform AuNRs were obtained by particle growth in solution, and BAC is found to stabilize the AuNRs for >1 year. The SERS activity of the resulting AuNRs is essentially identical to that of CTAB-protected nanorods. The SERS activity of the BAC protected nanorods was applied to the quantitative analysis of potato virus X (PVX). The calibration plot for PVX is linear in the 10 to 750 ng⋅mL −1 concentration range, and the detection limit is 2.2 ng⋅mL −1 . Graphical abstract SERS-active gold nanorods (AuNRs) have been prepared by using benzalkonium chloride as stabilization agent. Effects of chemical parameters on AuNRs have been explored and AuNRs were used in quantitative analysis of potato virus X (PVX).
ISSN:0026-3672
1436-5073
DOI:10.1007/s00604-017-2102-x