Clinical features of depressed patients with or without a family history of alcoholism

Objective:  To compare clinical features of depressed subjects without alcoholism but with a family history of alcoholism to a depressed group without alcoholism and without a family history of alcoholism. Method:  Clinical and demographic data of 209 depressed subjects without a history of alcoholi...

Full description

Saved in:
Bibliographic Details
Published in:Acta psychiatrica Scandinavica 2005-10, Vol.112 (4), p.266-271
Main Authors: Sher, L., Oquendo, M. A., Conason, A. H., Brent, D. A., Grunebaum, M. F., Zalsman, G., Burke, A. K., Mann, J. J.
Format: Article
Language:English
Subjects:
Addictive behaviors
Adult
Adult and adolescent clinical studies
Alcoholism
Alcoholism - genetics
Alcoholism - psychology
Biological and medical sciences
Child
child abuse
Child Abuse, Sexual
Comparative studies
Depression
Depressive Disorder - complications
Depressive Disorder - genetics
Depressive Disorder - psychology
Families & family life
family research
Female
Humans
Male
Medical sciences
Mental depression
Middle Aged
Mood disorders
Pedigree
post-traumatic stress disorder
Prevalence
Psychiatry
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Risk Factors
Stress Disorders, Post-Traumatic - etiology
Suicide
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Objective:  To compare clinical features of depressed subjects without alcoholism but with a family history of alcoholism to a depressed group without alcoholism and without a family history of alcoholism. Method:  Clinical and demographic data of 209 depressed subjects without a history of alcoholism in first‐degree relatives and 73 depressed individuals with a history of alcoholism in first‐degree relatives were compared. Subjects with a personal history of alcoholism were excluded. Results:  Depressed subjects with a family history of alcoholism have a significantly higher prevalence of reported childhood physical and sexual abuse and post‐traumatic stress disorder (PTSD), make more suicide attempts, and have greater intent to die at the time of their most lethal suicide attempt, compared to depressed subjects without a family history of alcoholism. Conclusion:  Depressed patients with a family history of alcoholism are at greater risk for suicidal behavior and PTSD and may require more careful management.
ISSN:0001-690X
1600-0447
DOI:10.1111/j.1600-0447.2005.00591.x