Colorimetric sensors for rapid detection of various analytes

Sensor technology for the rapid detection of the analytes with high sensitivity and selectivity has several challenges. Despite the challenges, colorimetric sensors have been widely accepted for its high sensitive and selective response towards various analytes. In this review, colorimetric sensors...

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Bibliographic Details
Published in:Materials Science & Engineering C 2017-09, Vol.78, p.1231-1245
Main Authors: Piriya V.S, Ajay, Joseph, Printo, Daniel S.C.G., Kiruba, Lakshmanan, Susithra, Kinoshita, Takatoshi, Muthusamy, Sivakumar
Format: Article
Language:English
Subjects:
Biocompatibility
Biomaterials
Biomedical materials
Biomolecules
Biosensor
Chemical compounds
Color
Colorimetric
Colorimetry
Deoxyribonucleic acid
Detection
DNA
Dyes
Fluorescence
Gases
Gold
Heavy metals
Interference
Materials science
Metal Nanoparticles
Metals
Molecular physics
Nanoparticles
Optical properties
Organic compounds
Radioisotopes
Selectivity
Sensitivity analysis
Sensor
Sensors
Silica
Silicon Dioxide
Silver
Studies
Surface Plasmon Resonance
Surgical implants
Technology assessment
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Summary:Sensor technology for the rapid detection of the analytes with high sensitivity and selectivity has several challenges. Despite the challenges, colorimetric sensors have been widely accepted for its high sensitive and selective response towards various analytes. In this review, colorimetric sensors for the detection of biomolecules like protein, DNA, pathogen and chemical compounds like heavy metal ions, toxic gases and organic compounds have been elaborately discussed. The visible sensing mechanism based on Surface Plasmon Resonance (SPR) using metal nanoparticles like Au, Ag, thin film interference using SiO2 and colorimetric array-based technique have been highlighted. The optical property of metal nanoparticles enables a visual color change during its interaction with the analytes owing to the dispersion and aggregation of nanoparticles. Recently, colorimetric changes using silica substrate for detection of protein and small molecules by thin film interference as a visible sensing mechanism has been developed without the usage of fluorescent or radioisotopes labels. Multilayer of biomaterials were used as a platform where reflection and interference of scattering light occur due to which color change happens leading to rapid sensing. Colorimetric array-based technique for the detection of organic compounds using chemoresponsive dyes has also been focused wherein the interaction of the analytes with the substrate coated with chemoresponsive dyes gives colorimetric change. [Display omitted] •Basic introduction about the sensor technology has been discussed.•Importance of colorimetric sensors for the detection of analytes has been overviewed.•Discussed in detail about the detection of various analytes like biomolecules and chemical compounds.•Colorimetric sensor detection based on nanoparticles and interference mechanism has been explained in detail.
ISSN:0928-4931
1873-0191
DOI:10.1016/j.msec.2017.05.018