Immunotherapy: Engineering Immunological Tolerance Using Quantum Dots to Tune the Density of Self‐Antigen Display (Adv. Funct. Mater. 22/2017)

In article number 1700290, Christopher M. Jewell and co‐workers use quantum dots (yellow) to track and control the display density of self‐molecules mistakenly attacked during autoimmune diseases. This precise display changes self‐molecule processing by antigen‐presenting cells (purple), reprogrammi...

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Bibliographic Details
Published in:Advanced functional materials 2017-06, Vol.27 (22), p.n/a
Main Authors: Hess, Krystina L., Oh, Eunkeu, Tostanoski, Lisa H., Andorko, James I., Susumu, Kimihiro, Deschamps, Jeffrey R., Medintz, Igor L., Jewell, Christopher M.
Format: Article
Language:English
Subjects:
Antigens
Autoimmune diseases
autoimmunity and tolerance
Disease control
Immunology
Lymphocytes
Materials science
modeling and simulation
Paralysis
Quantum dots
quantum dots and nanoparticles
T cell receptors
theranostics
vaccines and immunotherapy
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Summary:In article number 1700290, Christopher M. Jewell and co‐workers use quantum dots (yellow) to track and control the display density of self‐molecules mistakenly attacked during autoimmune diseases. This precise display changes self‐molecule processing by antigen‐presenting cells (purple), reprogramming the disease‐driving inflammatory T cells (red) to become regulatory T cells (developing white region on cell) that control disease and eliminate paralysis.
ISSN:1616-301X
1616-3028
DOI:10.1002/adfm.201770132