Effects of Vitamin E with Different Levels or Sources of Dietary Lipid on the Growth and Expression of Inflammatory, Oxidative Stress, and Apoptotic Genes in the Head Kidney of Olive Flounder, Paralichthys olivaceus

This study has assessed the effects of vitamin E (−E, +LE, +HE; 0, 100, 1000 mg/kg, respectively) in fish diets containing high levels (HL; 10%) of fish oil (FO) or mixed vegetable oils (VO) on the growth and inflammatory, oxidative stress, and apoptotic gene expression in the head kidney of olive f...

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Bibliographic Details
Published in:Journal of the World Aquaculture Society 2017-06, Vol.48 (3), p.518-530
Main Authors: Kim, Myoung‐Sug, Hur, Deok‐Hwe, Lee, Sang‐Min, Jeoung, Eunhee, Jeong, Hyun Do, Hong, Suhee
Format: Article
Language:English
Subjects:
Apoptosis
Body weight gain
Cytochrome
Cytochrome-c oxidase
Cytochromes
Diet
Fish
Fish diets
Fish oils
Gene expression
Genes
Growth
Inflammation
Interleukin 1
Interleukin 6
Interleukins
Kidneys
Lipids
Lysozyme
Marine fishes
Necrosis
Neoplasms
Oils & fats
Oxidase
Oxidative stress
Tocopherol
Transcription
Tumor necrosis factor
Tumor necrosis factor-TNF
Vegetable oils
Vitamin E
Vitamins
Weight gain
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Summary:This study has assessed the effects of vitamin E (−E, +LE, +HE; 0, 100, 1000 mg/kg, respectively) in fish diets containing high levels (HL; 10%) of fish oil (FO) or mixed vegetable oils (VO) on the growth and inflammatory, oxidative stress, and apoptotic gene expression in the head kidney of olive flounder, Paralichthys olivaceus. Consequently, the highest weight gain was achieved in the FO group and the lowest in the HL‐VO + LE group. The gene expression levels of each group were compared to the 5% FO group. The 5% VO group showed higher expression levels of tumor necrosis factor (TNF) α, interleukin (IL)‐1β, and scinderin‐like (ScinL) genes. Although lysozyme gene expression was higher in the HL‐VO + LE group, the other gene expression levels of the HL‐FO/VO + LE groups were not different from those of the FO group. The HL‐FO/VO−E/+HE groups showed a higher TNFα gene expression, but the cytochrome oxidase subunit III gene expression was higher in the HL‐FO−E and HL‐VO + HE groups. Lysozyme gene expression was higher in the HL‐FO−E and HL‐VO−E/+HE groups. IL‐6 and ScinL gene expression were higher in the HL‐VO‐E and HL‐VO + HE groups, respectively. In conclusion, mixed VO and too high or too low vitamin E levels in fish diets may affect inflammatory, oxidative stress, and apoptotic gene expression in the head kidney of olive flounder.
ISSN:0893-8849
1749-7345
DOI:10.1111/jwas.12359