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New synthesis of 4-alkyl-3-cyanocoumarins

A new procedure has been developed for the synthesis of 4-alkyl-6,8-dibromo-7-hydroxy-2-oxo-2 H -chromene-3-carbonitriles by bromination of 2-amino-4-alkyl-4 H -chromene-3-carbonitriles with bromine in acetic acid, followed by hydrolysis.

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Bibliographic Details
Published in:Russian journal of organic chemistry 2016, Vol.52 (7), p.983-986
Main Authors: Bardasov, I. N., Alekseeva, A. Yu, Malyshkina, N. L., Ershov, O. V., Surazhskaya, M. D., Grishanov, D. A.
Format: Article
Language:English
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Summary:A new procedure has been developed for the synthesis of 4-alkyl-6,8-dibromo-7-hydroxy-2-oxo-2 H -chromene-3-carbonitriles by bromination of 2-amino-4-alkyl-4 H -chromene-3-carbonitriles with bromine in acetic acid, followed by hydrolysis.
ISSN:1070-4280
1608-3393
DOI:10.1134/S1070428016070101