Multicomponent and domino reactions of 3-aroylacrylic acids in the synthesis of heterocycles

This review generalizes the data available on heterocyclizations of 3-aroylacrylic acids and their esters, published over the previous 15 years. Multicomponent, cascade, and domino reactions, as well as cycloaddition and electrocyclization reactions involving 3-aroylacrylic acids and their esters ha...

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Bibliographic Details
Published in:Chemistry of heterocyclic compounds (New York, N.Y. 1965) N.Y. 1965), 2016-09, Vol.52 (9), p.651-657
Main Authors: Beryozkina, Tetyana V., Kolos, Nadezhda N., Bakulev, Vasiliy A.
Format: Article
Language:English
Subjects:
Cascade chemical reactions
Chemistry
Chemistry and Materials Science
Esters
Organic Chemistry
Pharmacy
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Summary:This review generalizes the data available on heterocyclizations of 3-aroylacrylic acids and their esters, published over the previous 15 years. Multicomponent, cascade, and domino reactions, as well as cycloaddition and electrocyclization reactions involving 3-aroylacrylic acids and their esters have been used to obtain five- and six-membered aromatic and non-aromatic (including chiral) oxygen- or nitrogen-containing monocyclic heterocycles, spiro compounds, as well as condensed bi- and tricyclic systems.
ISSN:0009-3122
1573-8353
DOI:10.1007/s10593-016-1945-0