Gastric Juice Directly Enhanced IL-13-Induced CCL26 Expression in Human Bronchial Epithelial Cells in Vitro

Methods An immortalized human bronchial epithelial cell line (BEAS-2B) and normal human bronchial epithelial cells (NHBE) were exposed to acidic medium (pH 2) alone or with pepsin (gastric juice), followed by culture in normal medium in the presence or absence of IL-13.

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Bibliographic Details
Published in:Journal of allergy and clinical immunology 2017-02, Vol.139 (2), p.AB262-AB262
Main Authors: Orimo, Keisuke, MD, Futamura, Kyoko, MD, PhD, Okada, Naoko, PhD, Matsumoto, Kenji, MD, PhD
Format: Article
Language:English
Subjects:
Allergy and Immunology
Asthma
Firearm accidents & safety
Gastroesophageal reflux
Proteins
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Description
Summary:Methods An immortalized human bronchial epithelial cell line (BEAS-2B) and normal human bronchial epithelial cells (NHBE) were exposed to acidic medium (pH 2) alone or with pepsin (gastric juice), followed by culture in normal medium in the presence or absence of IL-13.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2016.12.846