Paediatric intra-axial posterior fossa tumours: pictorial review

Paediatric brain tumours commonly arise in the posterior cranial fossa. Early diagnosis is often challenging due to initial non-specific clinical symptoms, especially in very young children. The typical MR features of tumours in this region including medulloblastoma, ependymoma, juvenile pilocytic s...

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Bibliographic Details
Published in:Postgraduate medical journal 2013-01, Vol.89 (1047), p.39-46
Main Authors: Rasalkar, Darshana D, Chu, Winnie Chiu-wing, Paunipagar, Bhawan K, Cheng, Frankie W T, Li, C K
Format: Article
Language:English
Subjects:
Age
Astrocytoma - diagnosis
Biological and medical sciences
Brain cancer
Child
Child, Preschool
Cysts
Diffusion Magnetic Resonance Imaging - methods
Ependymoma - diagnosis
Female
General aspects
Glioma - diagnosis
Humans
Infratentorial Neoplasms - diagnosis
Infratentorial Neoplasms - pathology
Male
Medical prognosis
Medical sciences
Medulloblastoma - diagnosis
Metastasis
Rhabdoid Tumor - diagnosis
Tumors
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Summary:Paediatric brain tumours commonly arise in the posterior cranial fossa. Early diagnosis is often challenging due to initial non-specific clinical symptoms, especially in very young children. The typical MR features of tumours in this region including medulloblastoma, ependymoma, juvenile pilocytic subtype of cerebellar astrocytoma, brain stem glioma and atypical teratoid–rhabdoid tumour are illustrated. Diffusion-weighted imaging and apparent diffusion coefficient values combined with signal characteristics on conventional MR sequences can usually differentiate low-grade from high-grade tumours. Prompt diagnosis is crucial as total surgical resection, which is only possible in localised disease, improves prognosis. A practical MR flow chart is introduced for differentiating different types of posterior cranial fossa tumours, which might be useful in clinical practice.
ISSN:0032-5473
1469-0756
DOI:10.1136/postgradmedj-2011-130075