Impact of CARDIOrespiratory FITness on Arrhythmia Recurrence in Obese Individuals With Atrial Fibrillation

Abstract Background Obesity begets atrial fibrillation (AF). Although cardiorespiratory fitness is protective against incident AF in obese individuals, its effect on AF recurrence or the benefit of cardiorespiratory fitness gain is unknown. Objectives This study sought to evaluate the role of cardio...

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Bibliographic Details
Published in:Journal of the American College of Cardiology 2015-09, Vol.66 (9), p.985-996
Main Authors: Pathak, Rajeev K., MBBS, Elliott, Adrian, PhD, Middeldorp, Melissa E, Meredith, Megan, Mehta, Abhinav B., M Act St, Mahajan, Rajiv, MD, PhD, Hendriks, Jeroen M.L., PhD, Twomey, Darragh, MBBS, Kalman, Jonathan M., MBBS, PhD, Abhayaratna, Walter P., MBBS, PhD, Lau, Dennis H., MBBS, PhD, Sanders, Prashanthan, MBBS, PhD
Format: Article
Language:English
Subjects:
Age
atrial fibrillation
Cardiac arrhythmia
Cardiology
Cardiovascular
Colleges & universities
Exercise
fitness
Fitness equipment
Heart rate
Internal Medicine
Lifestyles
Lipids
Men
Metabolism
Mortality
Obesity
physical activity
Physical fitness
Risk factors
Weight control
weight loss
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Summary:Abstract Background Obesity begets atrial fibrillation (AF). Although cardiorespiratory fitness is protective against incident AF in obese individuals, its effect on AF recurrence or the benefit of cardiorespiratory fitness gain is unknown. Objectives This study sought to evaluate the role of cardiorespiratory fitness and the incremental benefit of cardiorespiratory fitness improvement on rhythm control in obese individuals with AF. Methods Of 1,415 consecutive patients with AF, 825 had a body mass index ≥27 kg/m2 and were offered risk factor management and participation in a tailored exercise program. After exclusions, 308 patients were included in the analysis. Patients underwent exercise stress testing to determine peak metabolic equivalents (METs). To determine a dose response, cardiorespiratory fitness was categorized as: low (100%). Impact of cardiorespiratory fitness gain was ascertained by the objective gain in fitness at final follow-up (≥2 METs vs.
ISSN:0735-1097
1558-3597
DOI:10.1016/j.jacc.2015.06.488