Regulatory T cells in chronic lymphocytic leukemia

Controversial results concerning the prognostic value of the regulatory T (Treg) cell percentage in peripheral blood of chronic lymphocytic leukemia (CLL) patients have been reported in the previous studies. This study aimed to estimate the prognostic relevance of Treg cells in untreated CLL patient...

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Bibliographic Details
Published in:Comparative clinical pathology 2015-05, Vol.24 (3), p.649-652
Main Authors: Aref, Salah, Azmy, Emaad, Hakim, Hazem, El Khodary, Tawfik, El Menshawy, Nadia, Ebrahim, Lamiaa
Format: Article
Language:English
Subjects:
Hematology
Medicine
Medicine & Public Health
Oncology
Original Article
Pathology
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Summary:Controversial results concerning the prognostic value of the regulatory T (Treg) cell percentage in peripheral blood of chronic lymphocytic leukemia (CLL) patients have been reported in the previous studies. This study aimed to estimate the prognostic relevance of Treg cells in untreated CLL patients at diagnosis. CLL patients showed significantly higher Treg cell percentage and Treg cell counts as compared to that identified in healthy normal controls ( P  
ISSN:1618-5641
1618-565X
DOI:10.1007/s00580-014-1961-3