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The overlapping and the correlation between D-dimer and C-reactive protein in patients with community-acquired pneumonia and pulmonary embolism
Coagulation abnormalities are present in pulmonary embolism (PE), but they are frequent in patients with severe infections, too. Elevated proinflammatory cytokines in patients with community-acquired pneumonia (CAP) lead to elevated D-dimer. We have analyzed plasma D-dimer and serum CRP in 37 patien...
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Published in: | International public health journal 2014-01, Vol.6 (1), p.41 |
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description | Coagulation abnormalities are present in pulmonary embolism (PE), but they are frequent in patients with severe infections, too. Elevated proinflammatory cytokines in patients with community-acquired pneumonia (CAP) lead to elevated D-dimer. We have analyzed plasma D-dimer and serum CRP in 37 patients with PE and 108 patients with CAP. The Pneumonia Severity Index was used to classify CAP patients into groups: Group I, Group II and Group III. Group IV, consisted of patients with PE. There was no CRP difference among the Group I and Group IV. Plasma D-dimer correlates with the severity of CAP. There were no differences in plasma D-dimer in the severe CAP and PE. The correlation between serum CRP and plasma D-dimer persist in non-severe CAP. D-dimer was higher in Group IV than in survivor CAP patients, but not higher than in non-survivor CAP patients. Positive correlation between CRP and D-dimer persists in non-severe CAP. In severe CAP, increases of Ddimer are influenced by inflammatory markers, accompanying diseases, patient's age and the severity of disease. |
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Elevated proinflammatory cytokines in patients with community-acquired pneumonia (CAP) lead to elevated D-dimer. We have analyzed plasma D-dimer and serum CRP in 37 patients with PE and 108 patients with CAP. The Pneumonia Severity Index was used to classify CAP patients into groups: Group I, Group II and Group III. Group IV, consisted of patients with PE. There was no CRP difference among the Group I and Group IV. Plasma D-dimer correlates with the severity of CAP. There were no differences in plasma D-dimer in the severe CAP and PE. The correlation between serum CRP and plasma D-dimer persist in non-severe CAP. D-dimer was higher in Group IV than in survivor CAP patients, but not higher than in non-survivor CAP patients. Positive correlation between CRP and D-dimer persists in non-severe CAP. In severe CAP, increases of Ddimer are influenced by inflammatory markers, accompanying diseases, patient's age and the severity of disease.</description><identifier>ISSN: 1947-4989</identifier><identifier>EISSN: 2374-1023</identifier><language>eng</language><publisher>Hauppauge: Nova Science Publishers, Inc</publisher><subject>Age ; Disease ; Drug therapy ; Embolisms ; Hemophilia ; Laboratories ; Medical prognosis ; Mortality ; Pneumonia ; Pregnancy ; Proteins</subject><ispartof>International public health journal, 2014-01, Vol.6 (1), p.41</ispartof><rights>Copyright Nova Science Publishers, Inc. 2014</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/1625577321/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$H</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/1625577321?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>315,786,790,21422,33646,43768,74578</link.rule.ids></links><search><creatorcontrib>Nastasijevic-Borovac, Desa</creatorcontrib><creatorcontrib>Petkovic, Tatjana Radjenovic</creatorcontrib><creatorcontrib>Pejcic, Tatjana</creatorcontrib><creatorcontrib>Stankovic, Ivana</creatorcontrib><title>The overlapping and the correlation between D-dimer and C-reactive protein in patients with community-acquired pneumonia and pulmonary embolism</title><title>International public health journal</title><description>Coagulation abnormalities are present in pulmonary embolism (PE), but they are frequent in patients with severe infections, too. 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Elevated proinflammatory cytokines in patients with community-acquired pneumonia (CAP) lead to elevated D-dimer. We have analyzed plasma D-dimer and serum CRP in 37 patients with PE and 108 patients with CAP. The Pneumonia Severity Index was used to classify CAP patients into groups: Group I, Group II and Group III. Group IV, consisted of patients with PE. There was no CRP difference among the Group I and Group IV. Plasma D-dimer correlates with the severity of CAP. There were no differences in plasma D-dimer in the severe CAP and PE. The correlation between serum CRP and plasma D-dimer persist in non-severe CAP. D-dimer was higher in Group IV than in survivor CAP patients, but not higher than in non-survivor CAP patients. Positive correlation between CRP and D-dimer persists in non-severe CAP. In severe CAP, increases of Ddimer are influenced by inflammatory markers, accompanying diseases, patient's age and the severity of disease.</abstract><cop>Hauppauge</cop><pub>Nova Science Publishers, Inc</pub></addata></record> |
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subjects | Age Disease Drug therapy Embolisms Hemophilia Laboratories Medical prognosis Mortality Pneumonia Pregnancy Proteins |
title | The overlapping and the correlation between D-dimer and C-reactive protein in patients with community-acquired pneumonia and pulmonary embolism |
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