If neurologists establish the diagnosis of Primary Sjogren's Syndrome?/ Norologlar nasil Primer Sjogren Sendromu tanisi koyar?

Introduction: Neurological involvements were shown in 20% of patients with Primary Sjogren's Syndrome (pSS). Neurological symptoms may be the first signs of pSS in 57% of the cases. In addition, early diagnosis and treatment of neurological disorders may save or improve the quality of life of t...

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Bibliographic Details
Published in:Noro-Psikiyatri Arsivi 2014-06, Vol.51 (2), p.148
Main Authors: Karaca, Sibel, Ersozlu Bozkirli, Emine Duygu, Karakurum Goksel, Basak, Tan, Meliha, Yucel, Ahmet Eftal
Format: Article
Language:English
Subjects:
Diagnosis
Nervous system
Neurologists
Physiological aspects
Practice
Sjogren's syndrome
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Summary:Introduction: Neurological involvements were shown in 20% of patients with Primary Sjogren's Syndrome (pSS). Neurological symptoms may be the first signs of pSS in 57% of the cases. In addition, early diagnosis and treatment of neurological disorders may save or improve the quality of life of these cases. There have been reports about the neurologic manifestations of pSS but little is known about the details of neurologically presented cases. Method: In this study, we described 11 pSS patients who presented with neurological manifestations. Results: Central nervous system (CNS) involvement was recorded in 7 (63.7%) and peripheric nervous system (PNS) involvement in 4 cases (36.4%). Conclusion: Our findings regarding the cases with neurological manifestations leading to the diagnosis of pSS suggest that: 1) The frequency of CNS involvement was higher than that of PNS, and the most frequent clinical pictures of CNS involvement are Multiple Sclerosis (MS)-like illnesses and optic neuritis, 2) Guillain Barre Syndrome (GBS) was the most frequent disease of PNS involvement; 3) Mononeuropathy multiplex (MM) might be the first sign of pSS; 4) Neurologists should consider pSS in the differential diagnosis of cases with MS, optic neuritis, GBS and neuropathies of unknown causes including MM; 5) There is an urgent need of therapeutical guidelines for the cases with neurological involvement associated with pSS. (Archives of Neuropsychiatry 2014; 51: 148-156) Key words: Primary Sjogren's syndrome (pSS), neurological manifestations, central nervous system (CNS), peripheral nervous system (PNS) Conflict of interest: The authors reported no conflict of interest related to this article. Giris: Primer Sjogren Sendromlu (PSS) hastalarin %20'sinde norolojik tutulum oldugu gosterilmistir. Olgularin %57'sinde ise ilk olarak norolojik belirtiler ortaya cikmaktadir. Norologlarin bu belirtileri erkenden tespit etmesi ve PSS tedavisine baslanmasi ile hastalarin yasami kurtarilabilmekte ve/veya yasam kalitesi arttirilabilmektedir. PSS ile iliskili norolojik hastaliklar oldukca iyi tanimlanmistir ancak norolojik bulgularla prezante olan olgularda PSS tanisi icin detayli bilgi bulunmamaktadir. Yontem: Bu calismada norolojik bulgular ile basvuran 11 hastada PSS tanimlanmistir. Bulgular: Yedi olguda (%63,7) merkezi sinir sistemi (CNS) tutulumu belirlenirken, 4 olguda (%36,4) periferik sinir sistemi (PNS) tutulumu saptanmistir. Sonuc: Norolojik hastaliklari nedeniyle PSS tanisi alan bu o
ISSN:1300-0667
1309-4866
DOI:10.4274/npa.y6911