Prediction of Coronary Artery Disease Severity Using CHADS2and CHA2DS2-VASc Scores and a Newly Defined CHA2DS2-VASc-HS Score

As the CHADS2and CHA2DS2-VASc scores include similar risk factors for the development of coronary artery disease (CAD), they may provide crucial information regarding the severity of coronary artery lesions and the risk of thromboembolism. To increase the likelihood of determining CAD severity, we f...

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Bibliographic Details
Published in:The American journal of cardiology 2014-03, Vol.113 (6), p.950
Main Authors: Cetin, Mustafa, Cakici, Musa, Zencir, Cemil, Tasolar, Hakan, Baysal, Erkan, Balli, Mehmet, Akturk, Erdal
Format: Article
Language:English
Subjects:
Acute coronary syndromes
Age
Cardiology
Cardiovascular disease
Cholesterol
Confidence intervals
Coronary vessels
Family medical history
Gender
Glucose
Heart attacks
Heart failure
Lipoproteins
Risk assessment
Risk factors
Smoking
Triglycerides
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Summary:As the CHADS2and CHA2DS2-VASc scores include similar risk factors for the development of coronary artery disease (CAD), they may provide crucial information regarding the severity of coronary artery lesions and the risk of thromboembolism. To increase the likelihood of determining CAD severity, we formulated the CHA2DS2-VASc-HS score comprising hyperlipidemia and smoking in addition to the components of the CHA2DS2-VASc score and male instead of female gender. We aimed to investigate whether these 3 risk scores can be used to predict CAD severity. A total of 407 consecutive patients who underwent coronary angiography were enrolled in the study. Presence of >50% stenosis in a coronary artery was assessed as significant CAD. Of the patients, 87 had normal coronary angiograms and served as group 1. The remaining 320 patients with coronary stenosis were further classified into 2 groups according to CAD with stenosis of =50%: 123 patients with mild CAD as group 2 and 197 patients with severe CAD as group 3. The CHADS2, CHA2DS2-VASc, and CHA2DS2-VASc-HS scores were significantly different among the 3 groups. The CHADS2, CHA2DS2-VASc, and CHA2DS2-VASc-HS scores correlated significantly with the number of diseased vessels (r = 0.406, p
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2013.11.056