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Synthesis of 1,3,4-Oxadiazole-Based Aromatic and Heterocyclic/Phenylpyrazole Derivatives
ABSTRACT A new series of 1,3,4‐oxadiazole‐based aromatic and heterocyclic/phenylpyrazole derivatives 6a–c, 7a–d, and 8 were synthesized via sequential 1,3‐dipolar cyclization, hydrazidation, benzoylation, dehydrative cyclization, and the Suzuki coupling reaction. Among the derivatives, compounds 7a...
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Published in: | Heteroatom chemistry 2014-05, Vol.25 (3), p.171-177 |
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Main Authors: | , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | ABSTRACT
A new series of 1,3,4‐oxadiazole‐based aromatic and heterocyclic/phenylpyrazole derivatives 6a–c, 7a–d, and 8 were synthesized via sequential 1,3‐dipolar cyclization, hydrazidation, benzoylation, dehydrative cyclization, and the Suzuki coupling reaction. Among the derivatives, compounds 7a and 7c with the corresponding 2‐thienyl and 2‐benzo[b]thienyl (Ar) at the phenyl group located at the N‐1 position of pyrazole showed a better conjugation range. |
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ISSN: | 1042-7163 1098-1071 |
DOI: | 10.1002/hc.21151 |