Lysophosphatidylserine (Lyso-PS) Made in Activated Neutrophils Enhances Their Clearance “Alive or Dead” by Macrophage Via Activation of a G2A to PKA to Rac Signaling Cascade: Implications for Restoring Normal Resolution of Neutrophilia in Chronic Granulomatous Disease (CGD)

Enhanced uptake was mediated through the g-protein coupled receptor G2A leading to PKA-dependent Rac activation.

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Bibliographic Details
Published in:Journal of allergy and clinical immunology 2010-02, Vol.125 (2), p.AB10-AB10
Main Authors: Bratton, D, Fernandez-Boyanapalli, R, Henson, P, Frasch, S.C
Format: Article
Language:English
Subjects:
Allergy and Immunology
Kinases
Rodents
Online Access:Get full text
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Description
Summary:Enhanced uptake was mediated through the g-protein coupled receptor G2A leading to PKA-dependent Rac activation.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2009.12.070