SINONASAL CANCER AND OCCUPATION: A CASE-CONTROL STUDY

In reviews of malignancy and occupation, cancer of the nose and paranasal sinuses (sinonasal cancer (SNC)) is frequently mentioned. In a case-control study of SNC among subjects who died in Connecticut in the period 1935–1975, occupations from death certificates and city directories were compared to...

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Bibliographic Details
Published in:American journal of epidemiology 1980-02, Vol.111 (2), p.183-193
Main Authors: ROUSH, GEORGE C., MEIGS, J. WISTER, KELLY, JoANN, FLANNERY, JOHN T., BURDO, HAROLD
Format: Article
Language:English
Subjects:
Adult
Aged
Connecticut
Dust
Humans
Male
Middle Aged
nickel
Nickel - adverse effects
nose neoplasms
Nose Neoplasms - chemically induced
Nose Neoplasms - epidemiology
occupational diseases
Occupational Diseases - chemically induced
Occupations
Oils - adverse effects
olls
Paranasal Sinus Neoplasms - chemically induced
Paranasal Sinus Neoplasms - epidemiology
Wood
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Summary:In reviews of malignancy and occupation, cancer of the nose and paranasal sinuses (sinonasal cancer (SNC)) is frequently mentioned. In a case-control study of SNC among subjects who died in Connecticut in the period 1935–1975, occupations from death certificates and city directories were compared to job titles taken from previous literature. The results do not support an association of the cancer with nickel (odds ratio = 0.7, 95% confidence limits (CL): 0.4, 1.5) but do support an association with cutting oils (odds ratio = 2.8, 95% CL: 1.4, 5.7) and wood dust (odds ratio = 4.0, 95% CL: 1.5, 10.8). Actual exposure to these agents was not documented, but the results were consistent with other features of the study and with previous ilterature. In a search for other occu pational correlates, SNC was also found to be positively associated with cut ters and with construction workers.
ISSN:0002-9262
1476-6256
DOI:10.1093/oxfordjournals.aje.a112886