Nanopores as protein sensors

Reporting in Nature Nanotechnology, Wei et al detect single proteins for the first time using solid-state nano-pores equipped with biological receptors. And in a recent paper in the Journal of the American Chemical Society, Rotem et al show how a protein nanopore, -hemolysin, can be rapidly reconfig...

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Bibliographic Details
Published in:	Nature biotechnology 2012-06, Vol.30 (6), p.506-507
Main Authors:	Howorka, Stefan, Siwy, Zuzanna S
Format:	Article
Language:	eng
Subjects:	Biomedical research Biosensing Techniques - instrumentation Biosensing Techniques - methods Biosensors Enzyme-Linked Immunosorbent Assay Models, Molecular Nanopores Nanotechnology Nanotechnology - instrumentation Proteins Proteins - analysis
Online Access:	Get full text
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Summary:	Reporting in Nature Nanotechnology, Wei et al detect single proteins for the first time using solid-state nano-pores equipped with biological receptors. And in a recent paper in the Journal of the American Chemical Society, Rotem et al show how a protein nanopore, -hemolysin, can be rapidly reconfigured to detect virtually any protein. Once such pores become readily available, they may compete with other protein-detection technologies for applications in diagnostics, environmental screening and research.
ISSN:	1087-0156 1546-1696