Helicobacter pylori infection and its associated factors among dyspepsia patients attending Debre Tabor Comprehensive Specialized Hospital, 2020

Helicobacter pylori is one of the most common bacterial infections of humankind that affects more than 50% of the world's population. It has been implicated as an important agent in the pathogenesis of peptic ulcer disease and gastric cancer. Data regarding its prevalence using stool antigen te...

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Bibliographic Details
Published in:PloS one 2023-03, Vol.18 (3), p.e0279396-e0279396
Main Authors: Jemere, Tadeg, Tilahun, Mekdes, Walle, Gashaw, Yideg, Getachew, Agegnehu, Assefa, Tilahun, Anemut, Abebe, Edget, Moges, Natnael
Format: Article
Language:English
Subjects:
Abdomen
Analysis
Antigens
Bacteria
Bacterial diseases
Bacterial infections
Biology and Life Sciences
Bivariate analysis
Care and treatment
Child
Cross-Sectional Studies
Data analysis
Data collection
Diagnosis
Distribution
Drinking water
Dyspepsia
Dyspepsia - complications
Dyspepsia - epidemiology
Earth Sciences
Ecology and Environmental Sciences
Ethics
Gastric cancer
Health aspects
Health risks
Helicobacter infections
Helicobacter Infections - complications
Helicobacter Infections - diagnosis
Helicobacter Infections - epidemiology
Helicobacter pylori
Hospitals, Special
Humans
Hygiene
Independent variables
Infection
Infections
Medical research
Medicine and Health Sciences
Medicine, Experimental
Overcrowding
Pathogenesis
People and Places
Peptic ulcer
Peptic ulcers
Population
Prevalence
Prevalence studies (Epidemiology)
Questionnaires
Regression analysis
Response rates
Risk factors
River water
Rivers
Sample size
Sampling techniques
Social Sciences
Sociodemographics
Socioeconomic factors
Statistical analysis
Stomach cancer
Ulcers
Variables
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Description
Summary:Helicobacter pylori is one of the most common bacterial infections of humankind that affects more than 50% of the world's population. It has been implicated as an important agent in the pathogenesis of peptic ulcer disease and gastric cancer. Data regarding its prevalence using stool antigen test is scarce in Ethiopia. Hence, the main aim of this study is to determine the prevalence of Helicobacter pylori infection among dyspeptic patients using stool antigen test and assessing the potential risk factors. Institution based cross-sectional study was conducted on 373 dyspepsia patients. Data were collected using a pre-tested interviewer administered questionnaire. SPSS Version 23 for Windows software was used for summarization and analyses of data. Bivariate analysis was conducted to detect the association between dependent and independent variables, and all candidate variables were entered into multivariate logistic regression. Statistical significance was set at p-value
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0279396