Gender based lung cancer risks for symptomatic coronary artery disease patients undergone cardiac CT

We estimate the lifetime attributable risk (LAR) of lung cancer incidence in symptomatic Coronary Artery Disease (CAD) patients receiving enhanced Coronary Computed Tomography Angiography (CCTA) and the unenhanced Computed Tomography Calcium Scoring (CTCS) examination. Retrospective analysis has bee...

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Bibliographic Details
Published in:PloS one 2022-04, Vol.17 (4), p.e0265609-e0265609
Main Authors: Dalah, Entesar Zawam, Obaideen, Abdulmunhem, Anam, Sabaa, Alzimami, Khalid, Jambi, Layal Khalid, Bradley, David A
Format: Article
Language:English
Subjects:
Adult
Angiography
Biology and Life Sciences
Cardiovascular disease
Complications and side effects
Computed tomography
Computed Tomography Angiography
Coronary Angiography - methods
Coronary artery
Coronary artery disease
Coronary Artery Disease - diagnostic imaging
Coronary Artery Disease - epidemiology
Coronary Artery Disease - etiology
Coronary heart disease
Coronary vessels
CT imaging
Demographic aspects
Dosage
Drug dosages
Esophagus
Evaluation
Female
Females
Gender
Health risks
Heart diseases
Humans
Lung cancer
Lung diseases
Lung Neoplasms - diagnostic imaging
Lung Neoplasms - epidemiology
Lung Neoplasms - etiology
Male
Mathematical analysis
Medical imaging
Medicine and Health Sciences
Patients
Physical Sciences
Physics
Radiation
Radiation Dosage
Radiation therapy
Radiology
Research and Analysis Methods
Retrospective Studies
Risk
Risk factors
Scanners
Statistical analysis
Statistical correlation
Tomography
Tomography, X-Ray Computed - methods
Vein & artery diseases
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Summary:We estimate the lifetime attributable risk (LAR) of lung cancer incidence in symptomatic Coronary Artery Disease (CAD) patients receiving enhanced Coronary Computed Tomography Angiography (CCTA) and the unenhanced Computed Tomography Calcium Scoring (CTCS) examination. Retrospective analysis has been made of CCTA and CTCS data collected for 87 confirmed CAD adult patients. Patient effective dose (E) and organ doses (ODs) were calculated using CT-EXPO. Statistical correlation and the differences between E and ODs in enhanced CCTA and unenhanced CTCS were calculated using the Pearson coefficient and Wilcoxon unpaired t-test. Following BEIR VII report guidance, organ-specific LARs for the cohort were estimated using the organ-equivalent dose-to-risk conversion factor for numbers of cases per 100,000 patients exposed to low doses of 0.1 Gy. Significant statistical difference (p
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0265609