Achievement of European Society of Cardiology/European Atherosclerosis Society lipid targets in very high-risk patients: Influence of depression and sex

To explore differences in the use of lipid lowering therapy and/or achievement of lipid guideline targets in patients with and without prior depression and influence of sex in very high-risk coronary patients. A retrospective observational cohort study was conducted using individual-level linked ele...

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Published in:PloS one 2022-02, Vol.17 (2), p.e0264529-e0264529
Main Authors: Ellins, Elizabeth A, Harris, Daniel E, Lacey, Arron, Akbari, Ashley, Torabi, Fatemeh, Smith, Dave, Jenkins, Geraint, Obaid, Daniel, Chase, Alex, John, Ann, Gravenor, Michael B, Halcox, Julian P
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Language:eng
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Sex
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Summary:To explore differences in the use of lipid lowering therapy and/or achievement of lipid guideline targets in patients with and without prior depression and influence of sex in very high-risk coronary patients. A retrospective observational cohort study was conducted using individual-level linked electronic health record data in patients who underwent percutaneous coronary intervention (2012-2017) in Wales. The cohort comprised of 13,781 patients (27.4% female), with 26.1% having prior depression. Lipid levels were recorded in 10,050 patients of whom 25% had depression. History of depression was independently associated with not having lipids checked (OR 0.79 95%CI 0.72-0.87 p
ISSN:1932-6203
1932-6203