Gender differences in predictors of intensive care units admission among COVID-19 patients: The results of the SARS-RAS study of the Italian Society of Hypertension

The global rate of intensive care unit (ICU) admission during the COVID-19 pandemic varies within countries and is among the main challenges for health care systems worldwide. Conflicting results have been reported about the response to coronavirus infection and COVID-19 outcomes in men and women. U...

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Bibliographic Details
Published in:PloS one 2020-10, Vol.15 (10), p.e0237297
Main Authors: Iaccarino, Guido, Grassi, Guido, Borghi, Claudio, Carugo, Stefano, Fallo, Francesco, Ferri, Claudio, Giannattasio, Cristina, Grassi, Davide, Letizia, Claudio, Mancusi, Costantino, Minuz, Pietro, Perlini, Stefano, Pucci, Giacomo, Rizzoni, Damiano, Salvetti, Massimo, Sarzani, Riccardo, Sechi, Leonardo, Veglio, Franco, Volpe, Massimo, Muiesan, Maria Lorenza
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Aged, 80 and over
Betacoronavirus - genetics
Biology and Life Sciences
Care and treatment
Congestive heart failure
Coronavirus Infections - epidemiology
Coronavirus Infections - virology
Coronaviruses
COVID-19
Critical care medicine
Cross-Sectional Studies
Demographic aspects
Diabetes
Female
Gender aspects
Gender differences
Health aspects
Health care
Heart diseases
Heart Failure
Hospitals
Humans
Hypertension
Infections
Intensive Care Units
Italy - epidemiology
Kidney diseases
Kidneys
Male
Medicine and Health Sciences
Men
Middle Aged
Mortality
Obesity
Pandemics
Patient Admission
Patients
Pneumonia, Viral - epidemiology
Pneumonia, Viral - virology
Regression analysis
Regression models
Renal Insufficiency, Chronic
Risk Factors
SARS-CoV-2
Severity of Illness Index
Sex differences
Sex differences (Biology)
Sex Factors
Viral diseases
Women
Womens health
Young Adult
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Summary:The global rate of intensive care unit (ICU) admission during the COVID-19 pandemic varies within countries and is among the main challenges for health care systems worldwide. Conflicting results have been reported about the response to coronavirus infection and COVID-19 outcomes in men and women. Understanding predictors of intensive care unit admission might be of help for future planning and management of the disease. We designed a cross-sectional observational multicenter nationwide survey in Italy to understand gender-related clinical predictors of ICU admission in patients with COVID-19. We analyzed information from 2378 charts of Italian patients certified for COVID-19 admitted in 26 hospitals. Three hundred ninety-five patients (16.6%) required ICU admission due to COVID19 infection, more frequently men (74%), with a higher prevalence of comorbidities (1,78±0,06 vs 1,54±0,03 p
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0237297