Possible link between dental diseases and arteriosclerosis in patients on hemodialysis

Patients on hemodialysis must undergo this procedure at a hospital three times weekly and might be unable to visit a dentist. In addition, dentists might hesitate to provide oral care because such patients tend to bleed because they are medicated with anticoagulants, are susceptible to bacterial inf...

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Bibliographic Details
Published in:PloS one 2019-12, Vol.14 (12), p.e0225038-e0225038
Main Authors: Misaki, Taro, Fukunaga, Akiko, Shimizu, Yoshitaka, Ishikawa, Akira, Nakano, Kazuhiko
Format: Article
Language:English
Subjects:
Age
Aged
Aged, 80 and over
Angina
Angina pectoris
Anticoagulants
Arteriosclerosis
Arteriosclerosis - epidemiology
Bacterial diseases
Bacterial infections
Biology and Life Sciences
Bleeding
Blood pressure
Cardiovascular diseases
Comorbidity
Comparative analysis
Complications
Consent
Coronary artery disease
Coronary heart disease
Dental caries
Dental Caries - epidemiology
Dental disorders
Dentistry
Dentists
Diabetes
Disease susceptibility
Female
Gum disease
Health aspects
Heart attack
Heart diseases
Hemodialysis
Hospitals
Humans
Infection
Informed consent
Kidney diseases
Kidney Failure, Chronic - epidemiology
Kidney Failure, Chronic - therapy
Male
Medicine and Health Sciences
Middle Aged
Mortality
Myocardial infarction
Nephrology
Oral Health
Patients
Periodontal diseases
Periodontal Diseases - epidemiology
Prevalence
Regression analysis
Renal Dialysis
Teeth
Transplants & implants
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Summary:Patients on hemodialysis must undergo this procedure at a hospital three times weekly and might be unable to visit a dentist. In addition, dentists might hesitate to provide oral care because such patients tend to bleed because they are medicated with anticoagulants, are susceptible to bacterial infections, and might have unusual drug reactions. We postulated that patients on hemodialysis have worse oral status than healthy people, which in turn might predispose such patients to systemic complications. We compared the status of dental caries and periodontal diseases among 80 patients on hemodialysis and 76 healthy individuals (controls) using the decayed, missing, or filled teeth (DMFT) index, total number of C4 teeth (destruction of the entire tooth crown), and periodontal pocket depth. Clinical data were analyzed after all patients on hemodialysis and controls provided written, informed consent to participate in the study. Total number of C4 teeth (p = 0.021), missing teeth (MT) index (p = 0.0302), and DMFT index score ≥ 24 (p = 0.017) were significantly higher in patients on hemodialysis than controls. Pulse pressure (p = 0.0042) and the prevalence of a history of heart disease such as angina pectoris and acute myocardial infarction (p = 0.029) were higher in patients on hemodialysis with higher (≥ 24) than lower (< 24) DMFT index scores. Periodontal pocket depth was not significantly different between these two groups. Worse status of dental caries is possibly associated with arteriosclerosis among patients on hemodialysis.
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0225038