Evaluation of the psychometric properties of the HIV Disability Questionnaire among adults living with HIV in the United Kingdom: A cross-sectional self-report measurement study

To evaluate the psychometric properties of the HIV Disability Questionnaire (HDQ) among people living with HIV (PLHIV) in London, United Kingdom (UK). This is a cross-sectional measurement study. We recruited and administered the self-reported HDQ, seven criterion measures, and a demographic questio...

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Bibliographic Details
Published in:PloS one 2019-07, Vol.14 (7), p.e0213222
Main Authors: Brown, Darren A, Simmons, Bryony, Boffito, Marta, Aubry, Rachel, Nwokolo, Nneka, Harding, Richard, O'Brien, Kelly K
Format: Article
Language:English
Subjects:
Acquired immune deficiency syndrome
Adult
Adults
Aged
Aging
AIDS
Analysis
Antiretroviral agents
Antiretroviral therapy
Biology and Life Sciences
Change detection
Cognitive ability
Confidence intervals
Consistency
Criteria
Cross-Sectional Studies
Dementia
Demographics
Disability Evaluation
Engineering and Technology
Health aspects
Highly active antiretroviral therapy
HIV
HIV Infections - drug therapy
HIV Infections - physiopathology
HIV Infections - psychology
HIV patients
Hospitals
Human immunodeficiency virus
Humans
Hypotheses
London
Male
Males
Median (statistics)
Medical diagnosis
Medicine and Health Sciences
Middle Aged
Palliative care
Physical therapy
Psychological aspects
Psychometrics
Quality of life
Quantitative psychology
Questionnaires
Rehabilitation
Reliability
Reproducibility of Results
Research and Analysis Methods
Self report
Self Report - statistics & numerical data
Signs and symptoms
Simmons, Rachel
Social Sciences
Statistical analysis
Surveys and Questionnaires - statistics & numerical data
Uncertainty
Validity
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Summary:To evaluate the psychometric properties of the HIV Disability Questionnaire (HDQ) among people living with HIV (PLHIV) in London, United Kingdom (UK). This is a cross-sectional measurement study. We recruited and administered the self-reported HDQ, seven criterion measures, and a demographic questionnaire with adults living with HIV accessing HIV care. We determined median and interquartile ranges (IQR) for disability presence, severity and episodic scores (range 0-100). We calculated Cronbach's alpha (α) Kuder-Richardson-20 (KR-20) statistics for disability and episodic scores respectively (internal consistency reliability), smallest detectable change (SDC) for each HDQ severity item and domain (precision), and tested 36 a priori hypotheses assessing correlations between HDQ and criterion scores (construct validity). Of N = 243 participants, all were male, median age 40 years, 94% currently taking antiretroviral therapy, and 22% living with ≥2 concurrent health conditions. Median HDQ domain scores ranged from 0 (IQR: 0,7) (difficulties with day-to-day activities domain) to 27 (IQR: 14, 41) (uncertainty domain). Cronbach's alpha for the HDQ severity scale ranged from 0.85 (95% Confidence Interval (CI): 0.80-0.90) in the cognitive domain to 0.93 (95%CI: 0.91-0.94) in the mental-emotional domain. The KR-20 statistic for the HDQ episodic scale ranged from 0.74 (95%CI: 0.66-0.83) in the cognitive domain to 0.91 (95%CI: 0.89-0.94) in the uncertainty domain. SDC ranged from 7.3-15.0 points on the HDQ severity scale for difficulties with day-to-day activities and cognitive symptoms domains, respectively. The majority of the construct validity hypotheses (n = 30/36, 83%) were confirmed. The HDQ possesses internal consistency reliability and construct validity with varied precision when administered to males living with HIV in London, UK. Clinicians and researchers may use the HDQ to measure the nature and extent of disability experienced by PLHIV in the UK, and to inform HIV service provision to address the health-related challenges among PLHIV.
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0213222