Anxiety, depression and quality of life in acute high risk cardiac disease patients eligible for wearable cardioverter defibrillator: Results from the prospective multicenter CRED-registry

Psychological distress is common in patients with cardiovascular disease and negatively impacts outcome. Psychological distress is high in acute high risk cardiac patients eligible for a WCD, and associated with low quality of life. Distress is aggravated by WCD. Consecutive patients eligible for a...

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Bibliographic Details
Published in:PloS one 2019-03, Vol.14 (3), p.e0213261-e0213261
Main Authors: Weiss, Michael, Michels, Guido, Eberhardt, Frank, Fehske, Wolfgang, Winter, Stefan, Baer, Frank, Choi, Yeong-Hoon, Albus, Christian, Steven, Daniel, Baldus, Stephan, Pfister, Roman
Format: Article
Language:English
Subjects:
Adult
Aged
Analysis
Anxiety
Anxiety Disorders - complications
Anxiety Disorders - diagnosis
Beta blockers
Biology and Life Sciences
Cardiac arrhythmia
Cardiac patients
Cardiomyopathy
Cardiovascular disease
Cardiovascular diseases
Cologne
Coronary artery disease
Coronary vessels
Defibrillators
Defibrillators, Implantable
Depression (Mood disorder)
Depressive Disorder - complications
Depressive Disorder - diagnosis
Engineering and Technology
Family medical history
Female
Health aspects
Health risks
Heart attacks
Heart diseases
Heart Diseases - complications
Heart Diseases - diagnosis
Heart Diseases - psychology
Heart failure
Hospitals
Humans
Implantable cardioverter-defibrillators
Internal medicine
Male
Medical prognosis
Medicine
Medicine and Health Sciences
Mental depression
Middle Aged
Mortality
Patients
Prospective Studies
Psychological aspects
Quality of Life
Registries
Risk
Signs and symptoms
Social Sciences
Wearable Electronic Devices
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Summary:Psychological distress is common in patients with cardiovascular disease and negatively impacts outcome. Psychological distress is high in acute high risk cardiac patients eligible for a WCD, and associated with low quality of life. Distress is aggravated by WCD. Consecutive patients eligible for a WCD were included in the prospective, multicenter "Cologne Registry of External Defibrillator" registry. Quality of life (Short Form-12), depressive symptoms (Beck-Depression Inventory II) and anxiety (State Trait Anxiety Inventory) were assessed at enrollment and 6-weeks, and associations with WCD prescription were analyzed. 123 patients (mean [SD] age 59 [± 14] years, 75% male) were included, 85 (69%) of whom received a WCD. At enrollment 21% showed clinically significant depressive symptoms and 52% anxiety symptoms, respectively. At 6 weeks, depressive and anxious symptoms significantly decreased to 7% and 25%, respectively. Depressive symptoms at enrollment and changes at 6 weeks showed significant associations with health-related quality of life, whereas anxious symptoms did not. There was a trend for better improvement of depression scores in patients with WCD (mean [SD] change in score points: -4.1 [6.1] vs -1.8 [3.9]; p = 0.09), whereas change of the anxiousness score was not different (-4.6 [9.5]) vs -3.7 [9.1], p = 0.68). In patients eligible for a WCD, depressive and anxiety symptoms were initially common and depressive symptoms showed a strong association with reduced health-related quality of life contributing to their clinical relevance. WCD recipients showed at least similar improvement of depression and anxiety at 6 weeks when compared to non recipients.
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0213261