Are Lipases Still Important Biocatalysts? A Study of Scientific Publications and Patents for Technological Forecasting

The great potential of lipases is known since 1930 when the work of J. B. S. Haldane was published. After eighty-five years of studies and developments, are lipases still important biocatalysts? For answering this question the present work investigated the technological development of four important...

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Bibliographic Details
Published in:PloS one 2015-06, Vol.10 (6), p.e0131624-e0131624
Main Authors: Daiha, Karina de Godoy, Angeli, Renata, de Oliveira, Sabrina Dias, Almeida, Rodrigo Volcan
Format: Article
Language:English
Subjects:
Animal Feed
Animals
Biocatalysis
Biocatalysts
Biodiesel fuels
Biofuels
Biotechnology - trends
Catalysis
Detergents
Detergents - chemical synthesis
Detergents - chemistry
Documents
Enzymes
Food
Food Industry
Food production
Forecasting
Formulations
Humans
Innovations
Intellectual property
Life cycle engineering
Life cycles
Lipase
Lipase - chemistry
Machine tool industry
Patent applications
Patents as Topic - statistics & numerical data
Pharmaceutical industry
Publications - statistics & numerical data
Scientific papers
Scientometrics
Technological forecasting
Technological planning
Technology
Web portals
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Summary:The great potential of lipases is known since 1930 when the work of J. B. S. Haldane was published. After eighty-five years of studies and developments, are lipases still important biocatalysts? For answering this question the present work investigated the technological development of four important industrial sectors where lipases are applied: production of detergent formulations; organic synthesis, focusing on kinetic resolution, production of biodiesel, and production of food and feed products. The analysis was made based on research publications and patent applications, working as scientific and technological indicators, respectively. Their evolution, interaction, the major players of each sector and the main subject matters disclosed in patent documents were discussed. Applying the concept of technology life cycle, S-curves were built by plotting cumulative patent data over time to monitor the attractiveness of each technology for investment. The results lead to a conclusion that the use of lipases as biocatalysts is still a relevant topic for the industrial sector, but developments are still needed for lipase biocatalysis to reach its full potential, which are expected to be achieved within the third, and present, wave of biocatalysis.
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0131624